Results 71 to 80 of about 88,697 (303)
, 2023 raw data INa ipsc (activation & inactivation) at ...
Kovalenko Sandaara, Frolova Sheida
core +1 more source
Material Coupling in Hybrid Neuromorphic Devices: From Fundamentals to System‐Level Applications
Advanced Functional Materials, EarlyView.Hybrid neuromorphic devices utilize heterointerfaces between emerging semiconductors, where charge transfer and trapping, ion or defect modulation, and photogating are translated into synaptic functions. This paper discusses coupling strategies that tailor interfacial electronic and ionic properties in organic semiconductors, metal oxides, two ...
Minsu So +5 more
wiley +1 more source
, 2023 Differentiation is the process where an unspecialized cell acquires cellular traits that allow it to perform specialized functions. Indeed, the actual potential of iPSCs rest in their direct differentiation to various types of somatic cells. In order to use iPSCs to treat disease or as research tools to study diseases, fully functioning specialized ...
openaire +2 more sources
Phenotyping iPSC-Vγ9Vδ2 T cells.
, 2019 iPSC-Vγ9Vδ2 T cells were generated from GDTA/NF-iPSC#1. Donor γδ T cells and donor NK cells were expanded from PBMCs of a healthy donor as controls.
Shin Yi Tang (6686252) +2 more
core +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
Advanced Healthcare Materials, EarlyView.This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Induced Pluripotent Stem Cell (iPSC)-derived Microglia for ALS modeling
Amyotrophic Lateral Sclerosis (ALS) is a progressive and fatal disease, primarily characterized by the degeneration of upper/lower motoneurons. ALS has a still incompletely understood etiopathology, but it is thought to be caused by the combination of ...
Silani V. +7 more
core +4 more sources
Stem Cell Research & Therapy, 2019 Background Metabolomics is the systemic study of the unique fingerprints of metabolites involved in cellular processes and biochemical reactions. The metabolomic approach is useful in diagnosing and predicting the development of rheumatoid arthritis (RA)
Juryun Kim +8 more
doaj +1 more source
iPSCs to the Rescue in Alzheimer's Research [PDF]
Cell Stem Cell, 2012 A crucial limitation to our understanding of Alzheimer's disease has been the inability to test hypotheses on live, patient-specific neurons. A recent study in Nature by Israel et al. (2012) reports that iPSC-derived neurons from AD patients recapitulate multiple aspects of disease pathology.
Choi, Se Hoon, Tanzi, Rudolph E.
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang +4 more
wiley +1 more source