Results 71 to 80 of about 59,069 (269)
Stem Cell Research, 2017 Heterozygous activating mutation (p.Glu227Lys) in KCNJ11 leads to maturity-onset diabetes of the young (MODY) type 13, that is a subtype of dominant inherited young-onset non-autoimmune diabetes due to a primary defect in pancreatic beta cells.
Frank Griscelli +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee +9 more
wiley +1 more source
Chondrogenic Differentiation from Induced Pluripotent Stem Cells Using Non-Viral Minicircle Vectors
Cells, 2020 : Human degenerative cartilage has low regenerative potential. Chondrocyte transplantation offers a promising strategy for cartilage treatment and regeneration.
Yeri Alice Rim +6 more
doaj +1 more source
Advanced Materials, EarlyView.SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung +6 more
wiley +1 more source
Reducing genomic instability in iPSCs
Oncotarget, 2015 Over the past 15 years, pluripotent cells, either embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs), became a formidable cellular platform to study developmental biology, model disease in vitro and pursue new drug discoveries. Furthermore, the promise of using endless cell derivatives from pluripotent cells to treat incurable ...
Ruiz S, Fernandez-Capetillo O
openaire +2 more sources
Artificial Synaptic Device Based on Self‐Aligned c‐In2O3 TFTs With an Ultrathin MgO Interlayer
Advanced Materials Technologies, EarlyView.A coplanar synaptic thin‐film transistor based on crystalline In2O3 is demonstrated using a PECVD SiO2 gate insulator and an ultrathin MgO interlayer. The MgO interlayer suppresses excessive carrier density and may facilitate proton‐related interfacial polarization, resulting in stable counterclockwise hysteresis and synaptic behavior.
Samiran Roy, Jewel Kumer Saha, Jin Jang
wiley +1 more source
Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids
Disease Models & Mechanisms, 2023 Jinlun Bai +8 more
doaj +1 more source
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
Maturing iPSC-Derived Cardiomyocytes [PDF]
Cells, 2020 Cardiovascular disease is a major cause of mortality worldwide [...]
openaire +3 more sources