Results 81 to 90 of about 88,697 (303)
When Fibroblasts MET iPSCs [PDF]
Cell Stem Cell, 2010 Two independent studies by Li et al. (2010) and Samavarchi-Tehrani et al. (2010) in this issue of Cell Stem Cell suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming ...
Polo, Jose M., Hochedlinger, Konrad
openaire +2 more sources
Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms
Advanced Healthcare Materials, EarlyView.Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet +11 more
wiley +1 more source
Stem Cell Research, 2020 Human induced pluripotent stem cells (iPSCs) that express stable and robust fluorescent proteins have proven to be indispensable in basic and translational research.
Kira Patterson +3 more
doaj +1 more source
Application of a Magnetic Platform in α6 Integrin-Positive iPSC-TM Purification
, 2023 The emergence of induced pluripotent stem cell (iPSC) technology has provided a new approach to regenerating decellularized trabecular meshwork (TM) in glaucoma.
Pengchao Feng +9 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Using a tooth‐on‐a‐chip model that recreates interactions between dental epithelial and mesenchymal cells, the authors show that sequential FGF10+BMP4, BMP2, and Emdogain produce distinct, biologically consistent regenerative responses. The platform recapitulates known signal‐specific effects and, for the first time, reveals an influence of Emdogain on
Chong Huang +3 more
wiley +1 more source
Trend of critical minerals utilization for Indonesia’s Sustainable Energy Transition: A review [PDF]
E3S Web of ConferencesThe European Union calculates supplies of essential minerals using an economic significance index, a supply risk index and an environmental risk index. The U.S.
Sasongko Nugroho Adi +3 more
doaj +1 more source
, 2023 Differentiation is the process where an unspecialized cell acquires cellular traits that allow it to perform specialized functions. Indeed, the actual potential of iPSCs rest in their direct differentiation to various types of somatic cells. In order to use iPSCs to treat disease or as research tools to study diseases, fully functioning specialized ...
openaire +2 more sources
Cell & Bioscience, 2017 Induced pluripotent stem cells (iPSCs) hold great promises in cell therapy. However, the potential safety issues have dampened the enthusiasm of their clinical development. One of the biggest concerns came from the observations that genomic alterations exist in iPSCs.
Hualong Yan, Yun-Bo Shi, Jing Huang
openaire +3 more sources
Transplantation of purified iPSC-derived cardiomyocytes in myocardial infarction [PDF]
, 2017 BACKGROUND:Induced pluripotent stem cells (iPSC) can be differentiated into cardiomyocytes and represent a possible autologous cell source for myocardial repair.
Sebastian V. Rojas +20 more
core +1 more source
Advanced Materials, EarlyView.A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen +8 more
wiley +1 more source