Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. [PDF]
Non-human primates (NHPs) can serve as a human-like model to study cell therapy using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). However, whether the efficacy of NHP and human iPSC-CMs is mechanistically similar remains unknown.
Aguirre, Aitor +19 more
core +6 more sources
Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector [PDF]
Human pluripotent stem cells (PSCs) are widely used for in vitro disease modeling. One of the challenges in the field is represented by the ability of converting human PSCs into specific disease-relevant cell types.
De Santis, Riccardo +5 more
core +9 more sources
Natural disasters and COVID-19: health worker preparedness and response [PDF]
The purpose of this study was to determine the preparedness of health workers individually and in the workplace to deal with natural disasters during COVID-19.
Wahyuni Dewi +4 more
doaj +1 more source
Novel Approaches to Program Cells to Differentiate into Cardiomyocytes in Myocardial Regeneration
With heart failure (HF) being one of the leading causes of hospitalization and death worldwide, multiple stem cell therapies have been attempted to accelerate the regeneration of the infarct zone.
Victor Bonavida +5 more
doaj +1 more source
Balla ewako: community response to the COVID-19 pandemic based on local wisdom [PDF]
The COVID-19 pandemic has entered a new phase with the discovery of new variants from several countries entering Indonesia. This epidemic is capable of destroying the joints of people's lives, such as health, education, politics, economics, social ...
Fatkul Fikri Ahmad +4 more
doaj +1 more source
Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- and method-dependent [PDF]
Induced pluripotent stem cell (iPSC)‐derived retinal organoids provide a platform to study human retinogenesis, disease modeling, and compound screening.
Armstrong, Lyle +7 more
core +2 more sources
Generation of donor organs in chimeric animals via blastocyst complementation
The lack of organs for transplantation is an important problem in medicine today. The growth of organs in chimeric animals may be the solution of this.
T. I. Babochkina +2 more
doaj +1 more source
Determination of tsunami run-up and golden time in the megathrust subduction zone of the sunda strait segment [PDF]
The Indonesian Disaster Data and Information Management Database state that the tsunami in the Megathrust Subduction Zone of the Sunda Strait Segment is a disaster threat with high impact and loss of life every time it occurs.
Sarikanti Ponangsera Iko +3 more
doaj +1 more source
CiRA iPSC seed stocks (CiRA's iPSC Stock Project)
In Japan, induced pluripotent stem cell (iPSC) Stock Project has started from 2013. The goal of the Project is to manufacture and release clinical-grade HLA homozygous iPSC lines that can cover almost the entire of Japanese population. We show the summary of the cell lines distributed, test results for quality control and future plans.
Tadaaki Hanatani, Naoko Takasu
openaire +3 more sources
Pluripotent Stem Cell-Based Models: A Peephole into Virus Infections during Early Pregnancy
The rubella virus (RV) was the first virus shown to be teratogenic in humans. The wealth of data on the clinical symptoms associated with congenital rubella syndrome is in stark contrast to an incomplete understanding of the forces leading to the ...
Claudia Claus +2 more
doaj +1 more source

