Results 21 to 30 of about 88,697 (303)

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability [PDF]

, 2015
This work has been supported by: Motor Neurone Disease Association (G.B.M., S.C. and C.E.S.); Euan MacDonald Centre (G.B.M. and S.C.); European Research Council (L.V.); Cambridge Hospitals National Institute for Health Research Biomedical Research Center
Foster, Joshua D., Shaw, Christopher E., Cleary, Elaine M., Cleary, Elaine M, Foster, Joshua D, Miles, Gareth B, Devlin, Anna-Claire, Geti, Imbisaat, Cleary, Elaine Marie, Miles, Gareth B., Borooah, Shyamanga, Devlin, Anna Claire, Shaw, Christopher E, Vallier, Ludovic, Burr, Karen, Chandran, Siddharthan, Miles, Gareth B; id_orcid   +16 more
core   +1 more source

iPSC-CVPC-specific exons enriched for splice sites overlapping motifs of 122 RBPs.

, 2022
Shown are the differences in the likelihood of the 100 bp upstream of the acceptor splice sites of iPSC-CVPC-specific, adult heart-specific and adult arteria-specific exons to harbor motifs of 122 RBPs.
Agnieszka D’Antonio-Chronowska (12161087), Kelly A. Frazer (11577020), Matteo D’Antonio (12161078), Hiroko Matsui (8140410), Margaret K. R. Donovan (12161084), Jennifer P. Nguyen (10051683), Timothy D. Arthur (12161081)   +6 more
core   +1 more source

Earthquake and tsunami potential levels in Sulawesi (lesson learned earthquake West Sulawesi) [PDF]

E3S Web of Conferences, 2021
Earthquake and tsunami disasters always bring negative impacts and losses for humans. The high frequency of earthquake disasters in Sulawesi and the massive impact of destruction and damage to infrastructure, loss of homes and property, and death of ...
Khoirudin Apriyadi Rio, Sutisna Sobar, Lasmono, Tri Januarti Riskina   +3 more
doaj   +1 more source

Extracellular Vesicles Derived from Induced Pluripotent Stem Cells Promote Renoprotection in Acute Kidney Injury Model

Cells, 2020
Induced pluripotent stem cells (iPSC) have been the focus of several studies due to their wide range of application, including in cellular therapy. The use of iPSC in regenerative medicine is limited by their tumorigenic potential. Extracellular vesicles
Federica Collino, Jarlene A. Lopes, Marta Tapparo, Giovane G. Tortelote, Taís H. Kasai-Brunswick, Gustavo M.C. Lopes, Douglas B. Almeida, Renata Skovronova, Camila H. C. Wendt, Kildare R. de Miranda, Benedetta Bussolati, Adalberto Vieyra, Rafael Soares Lindoso   +12 more
doaj   +1 more source

Spinal muscular atrophy patient iPSC-derived motor neurons have reduced expression of proteins important in neuronal development [PDF]

, 2016
This work was supported by The RJAH Institute of Orthopaedics, UK (H.F.), The SMA Trust, UK (H.F.), Cedars-Sinai Institutional startup funds (D.S), California Institute for Regenerative Medicine Grant RT-02040 (D.S.), National Center for Advancing ...
Heidi R. Fuller, Andrew R. Gross, Kaus, Anjoscha, Morris, Glen, Sareen, Dhruv, Glenn E. Morris, Fuller, H, Shirran, Sally Lorna, Catherine H. Botting, Shirran, SL, Botting, Catherine Helen, Dhruv Sareen, Mandefro, Berhan, Botting, CH, Gross, AR, Berhan Mandefro, Fuller, Heidi, Sally L. Shirran, Sareen, S, Morris, GE, Anjoscha S. Kaus, Gross, Andrew, Mandefro, B, Kaus, AS, Andrew R Gross, Heidi R Fuller, Catherine H Botting, Berhan eMandefro, Sally L Shirran, Anjoscha Samija Kaus, Fuller, HR, Dhruv eSareen, Glenn E Morris, Shirran, Sally Lorna; id_orcid   +33 more
core   +1 more source

Interactome Analysis of iPSC Secretome and Its Effect on Macrophages In Vitro. [PDF]

, 2021
Induced pluripotent stem cell secretome (iPSC-CM) mitigate organ injury and help in repair. Macrophages play a critical role in tissue repair and regeneration and can be directed to promote tissue repair by iPSC-CM, although the exact mechanisms are not ...
Fabienne Caldana, Tamò, Luca, Caldana, Fabienne, Simillion, Cedric, Thomas Geiser, Nita, Izabela, Heller, Manfred, Geiser, Thomas, Gazdhar, Amiq, Fytianos, Kleanthis, Feki, Anis, Izabela Nita, Amiq Gazdhar, Anis Feki, Kleanthis Fytianos, Cedric Simillion, Manfred Heller, Luca Tamò   +17 more
core   +2 more sources

Banking on iPSC- Is it Doable and is it Worthwhile [PDF]

Stem Cell Reviews and Reports, 2014
El descubrimiento de células madre pluripotentes inducidas (iPSC) y el desarrollo simultáneo de protocolos para su diferenciación específica de tipo celular han revolucionado los estudios de enfermedades y han planteado la posibilidad de que se pueda lograr una medicina personalizada.
Susan L. Solomon, Fernando J. Pitossi, Mahendra S. Rao   +2 more
openaire   +3 more sources

iPSC-EC H3K27Ac ChiP-Seq

, 2017
ChIP-Seq for H3K27Ac in iPSC ...
Raj Gupta (7003349)
core   +2 more sources

The Challenge of Bringing iPSCs to the Patient [PDF]

International Journal of Molecular Sciences, 2019
The implementation of induced pluripotent stem cells (iPSCs) in biomedical research more than a decade ago, resulted in a huge leap forward in the highly promising area of personalized medicine. Nowadays, we are even closer to the patient than ever.
María del Carmen Ortuño-Costela, Victoria Cerrada, Marta García-López, M. Esther Gallardo   +3 more
openaire   +4 more sources

iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes

, 2023
Poster by Noura Aldous, Ahmed Elsayed, Nehad Alajez, and Essam M. Abdelalim (Hamad Bin Khalifa University) Background: Generation of pancreatic beta cells from human pluripotent stem cells (hPSCs) is a promising approach for studying diabetes ...
Noura Aldous (15429873), Ahmed Elsayed (10311269), Essam M. Abdelalim (14152596), Nehad Alajez (3563309)   +3 more
core   +1 more source