Banking on iPSC- Is it Doable and is it Worthwhile [PDF]
El descubrimiento de células madre pluripotentes inducidas (iPSC) y el desarrollo simultáneo de protocolos para su diferenciación específica de tipo celular han revolucionado los estudios de enfermedades y han planteado la posibilidad de que se pueda lograr una medicina personalizada.
Susan L. Solomon +2 more
openaire +3 more sources
Phenotyping Neurodegeneration in Human iPSCs [PDF]
Induced pluripotent stem cell (iPSC) technology holds promise for modeling neurodegenerative diseases. Traditional approaches for disease modeling using animal and cellular models require knowledge of disease mutations. However, many patients with neurodegenerative diseases do not have a known genetic cause.
Li, Jonathan, Fraenkel, Ernest
openaire +4 more sources
Pentahelix synergity natural and non-natural disaster management in Pidie Jaya District Aceh Province to support national security [PDF]
Geographically, Indonesia is located on disaster prone area. Natural disasters such as earthquakes, tsunamis, floods, landslides, volcanic eruptions and non-natural disaster such as Covid-19 Pandemic often occur in various places in Indonesia including ...
Yulianto Sugeng +3 more
doaj +1 more source
The Challenge of Bringing iPSCs to the Patient [PDF]
The implementation of induced pluripotent stem cells (iPSCs) in biomedical research more than a decade ago, resulted in a huge leap forward in the highly promising area of personalized medicine. Nowadays, we are even closer to the patient than ever.
María del Carmen Ortuño-Costela +3 more
openaire +4 more sources
Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages [PDF]
Induced pluripotent stem cells (iPSCs) offer great promise for the field of regenerative medicine, and iPSC-derived cells have already been applied in clinical practice. However, potential contamination of effector cells with residual pluripotent cells (e.g., teratoma-initiating cells) or effector cell-associated side effects may limit this approach ...
Alexandra Lipus +11 more
openaire +3 more sources
Human pluripotent stem cells offer a limitless source of cells for regenerative medicine. They are also highly valuable as tools to study development and pathologies or as cellular substrates to screen and test new drugs.
Eddy Quelennec +5 more
doaj +1 more source
Earthquake and tsunami potential levels in Sulawesi (lesson learned earthquake West Sulawesi) [PDF]
Earthquake and tsunami disasters always bring negative impacts and losses for humans. The high frequency of earthquake disasters in Sulawesi and the massive impact of destruction and damage to infrastructure, loss of homes and property, and death of ...
Khoirudin Apriyadi Rio +3 more
doaj +1 more source
Background Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the elderly, resulting in gradual destruction of cognitive abilities.
Hyunkyung Mo +7 more
doaj +1 more source
Anti-fibrotic effect of a selective estrogen receptor modulator in systemic sclerosis
Background The rarity of systemic sclerosis (SSc) has hampered the development of therapies for this intractable autoimmune disease. Induced pluripotent stem cell (iPSC) can be differentiated into the key disease-affected cells in vitro.
Yena Kim +3 more
doaj +1 more source
Improving food security through the urban farming workshop for disaster risk reduction: evidence from Jogoyudan Village, Yogyakarta as a Resilient City [PDF]
This study aims to determine the effect of the implementation of urban farming workshops on food security of Jogoyudan Village residents supporting the concept of Yogyakarta as a Resilient City as a disaster risk reduction.
Jalu Aji Lexi +4 more
doaj +1 more source

