Results 31 to 40 of about 116,955 (355)

ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons [PDF]

open access: yes, 2015
Patient-derived induced Pluripotent Stem Cells (iPSCs) provide an opportunity to study human diseases mainly in those cases where no suitable model systems are available.
Bozzoni, Irene   +9 more
core   +4 more sources

Pentahelix synergity natural and non-natural disaster management in Pidie Jaya District Aceh Province to support national security [PDF]

open access: yesE3S Web of Conferences, 2021
Geographically, Indonesia is located on disaster prone area. Natural disasters such as earthquakes, tsunamis, floods, landslides, volcanic eruptions and non-natural disaster such as Covid-19 Pandemic often occur in various places in Indonesia including ...
Yulianto Sugeng   +3 more
doaj   +1 more source

Banking on iPSC- Is it Doable and is it Worthwhile [PDF]

open access: yesStem Cell Reviews and Reports, 2014
El descubrimiento de células madre pluripotentes inducidas (iPSC) y el desarrollo simultáneo de protocolos para su diferenciación específica de tipo celular han revolucionado los estudios de enfermedades y han planteado la posibilidad de que se pueda lograr una medicina personalizada.
Susan L. Solomon   +2 more
openaire   +3 more sources

The Challenge of Bringing iPSCs to the Patient [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
The implementation of induced pluripotent stem cells (iPSCs) in biomedical research more than a decade ago, resulted in a huge leap forward in the highly promising area of personalized medicine. Nowadays, we are even closer to the patient than ever.
María del Carmen Ortuño-Costela   +3 more
openaire   +4 more sources

Anti-fibrotic effect of a selective estrogen receptor modulator in systemic sclerosis

open access: yesStem Cell Research & Therapy, 2022
Background The rarity of systemic sclerosis (SSc) has hampered the development of therapies for this intractable autoimmune disease. Induced pluripotent stem cell (iPSC) can be differentiated into the key disease-affected cells in vitro.
Yena Kim   +3 more
doaj   +1 more source

Intranasal administration of induced pluripotent stem cell-derived cortical neural stem cell-secretome as a treatment option for Alzheimer’s disease

open access: yesTranslational Neurodegeneration, 2023
Background Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the elderly, resulting in gradual destruction of cognitive abilities.
Hyunkyung Mo   +7 more
doaj   +1 more source

Improving food security through the urban farming workshop for disaster risk reduction: evidence from Jogoyudan Village, Yogyakarta as a Resilient City [PDF]

open access: yesE3S Web of Conferences, 2021
This study aims to determine the effect of the implementation of urban farming workshops on food security of Jogoyudan Village residents supporting the concept of Yogyakarta as a Resilient City as a disaster risk reduction.
Jalu Aji Lexi   +4 more
doaj   +1 more source

Hybrid integrated platform of PDMS microfluidics and silica capillary for effective CE and ESI-MS coupling [PDF]

open access: yes, 2009
We present an effective hybrid integration of PDMS microfluidic devices and fused silica capillaries. These hybrid microfluidic integrated PDMS and silica capillary (iPSC) modules exhibit a novel architecture and method for leakage free CE sample ...
Dimov, Ivan Krastev   +3 more
core   +1 more source

iPSCs: Unstable Origins?

open access: yesMolecular Therapy, 2011
The advent of induced pluripotent stem cell (iPSC) technology holds great promise to revolutionize personalized cell-based therapies.1,2,3,4,5 Recent advances in gene transfer technology therefore open up exciting possibilities for efficient and safe genetic modification of autologous cells in this context.6 As potential therapeutic applications are ...
Mukherjee, Sayandip, Thrasher, Adrian J
openaire   +2 more sources

iPSCs in Modeling and Therapy of Osteoarthritis [PDF]

open access: yesBiomedicines, 2021
Osteoarthritis (OA) belongs to chronic degenerative disorders and is often a leading cause of disability in elderly patients. Typically, OA is manifested by articular cartilage erosion, pain, stiffness, and crepitus. Currently, the treatment options are limited, relying mostly on pharmacological therapy, which is often related to numerous complications.
Maria Csobonyeiova   +4 more
openaire   +3 more sources

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