Results 31 to 40 of about 88,697 (303)
Stem Cell Research, 2020 Human pluripotent stem cells offer a limitless source of cells for regenerative medicine. They are also highly valuable as tools to study development and pathologies or as cellular substrates to screen and test new drugs.
Eddy Quelennec +5 more
doaj +1 more source
Phenotyping Neurodegeneration in Human iPSCs [PDF]
Annual Review of Biomedical Data Science, 2021 Induced pluripotent stem cell (iPSC) technology holds promise for modeling neurodegenerative diseases. Traditional approaches for disease modeling using animal and cellular models require knowledge of disease mutations. However, many patients with neurodegenerative diseases do not have a known genetic cause.
Li, Jonathan, Fraenkel, Ernest
openaire +4 more sources
Model system dynamics potential impact of disasters due to the re-period of the October 25th, 2010 earthquake in the Mentawai Islands [PDF]
E3S Web of Conferences, 2021 Geographically, the Mentawai Islands Regency has a territorial boundary with the sea. The north side is the Siberut Strait, the south side is bordered by the Indian Ocean, the east side is bordered by the Mentawai Strait, and the west side is bordered by
Aprilyanto +3 more
doaj +1 more source
Pentahelix synergity natural and non-natural disaster management in Pidie Jaya District Aceh Province to support national security [PDF]
E3S Web of Conferences, 2021 Geographically, Indonesia is located on disaster prone area. Natural disasters such as earthquakes, tsunamis, floods, landslides, volcanic eruptions and non-natural disaster such as Covid-19 Pandemic often occur in various places in Indonesia including ...
Yulianto Sugeng +3 more
doaj +1 more source
Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages [PDF]
International Journal of Molecular Sciences, 2020 Induced pluripotent stem cells (iPSCs) offer great promise for the field of regenerative medicine, and iPSC-derived cells have already been applied in clinical practice. However, potential contamination of effector cells with residual pluripotent cells (e.g., teratoma-initiating cells) or effector cell-associated side effects may limit this approach ...
Alexandra Lipus +11 more
openaire +3 more sources
scRNA-seq on iPSC-derived microglia
, 2023 scRNA-seq of iPSC-microglia (pseudo-bulk) Pseudo-bulk from processed single-cell RNA-seq data from uninfected iPSC-derived microglia (comprising protein-coding genes).
Carl Herrmann (6582830) +5 more
core +1 more source
Translational Neurodegeneration, 2023 Background Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the elderly, resulting in gradual destruction of cognitive abilities.
Hyunkyung Mo +7 more
doaj +1 more source
Improving food security through the urban farming workshop for disaster risk reduction: evidence from Jogoyudan Village, Yogyakarta as a Resilient City [PDF]
E3S Web of Conferences, 2021 This study aims to determine the effect of the implementation of urban farming workshops on food security of Jogoyudan Village residents supporting the concept of Yogyakarta as a Resilient City as a disaster risk reduction.
Jalu Aji Lexi +4 more
doaj +1 more source
Molecular Therapy, 2011 The advent of induced pluripotent stem cell (iPSC) technology holds great promise to revolutionize personalized cell-based therapies.1,2,3,4,5 Recent advances in gene transfer technology therefore open up exciting possibilities for efficient and safe genetic modification of autologous cells in this context.6 As potential therapeutic applications are ...
Mukherjee, Sayandip, Thrasher, Adrian J
openaire +2 more sources
Anti-fibrotic effect of a selective estrogen receptor modulator in systemic sclerosis
Stem Cell Research & Therapy, 2022 Background The rarity of systemic sclerosis (SSc) has hampered the development of therapies for this intractable autoimmune disease. Induced pluripotent stem cell (iPSC) can be differentiated into the key disease-affected cells in vitro.
Yena Kim +3 more
doaj +1 more source