Results 11 to 20 of about 4,432 (206)

Discrepancies Between Recommendations in Evidence-Based Guidelines for the Management of Obesity in Adolescents and Adults: An Evidence Map. [PDF]

Obes Rev
ABSTRACT Background/Aim The aim of this evidence map is to provide a systematic overview of evidence‐based guidelines for the management of obesity and to highlight discrepancies between recommendations for the pediatric and adult populations. Knowing about these discrepancies may be relevant during the transition from pediatrics to adult healthcare to
Brauchmann J, Laudenbach L, Kapp P, Grummich K, Lischka J, Vanersa N, Rocha EPAA, Ernst G, Meerpohl JJ, Tannen A, Weghuber D, Weihrauch-Blüher S, Wiegand S, Torbahn G.   +13 more
europepmc   +2 more sources

Real-world clinical practice in health technology assessment: state of the art for 2022

Реальная клиническая практика: данные и доказательства, 2023
The real-world data are used in drug authorization procedures, comparative efficacy and safety research, to make changes in the Summary of Product Characteristics, clinical recommendations.
A. A. Kurylev, A. A. Zhuravkov, A. S. Kolbin   +2 more
doaj   +1 more source

Analyse von Orphan-Drug-Verfahren in der frühen Nutzenbewertung: RCTs versus best-verfügbare vergleichende Evidenz

Monitor Versorgungsforschung, 2023
Zur Beurteilung der Wirksamkeit und Sicherheit eines neuen Wirkstoffes ist für die europäische Zulassungsbehörde (European Medicines Agency, EMA) die randomisierte kontrollierte Studie (RCT) der Goldstandard.
Dr. rer. nat. Gerrit Müller, Dr. rer. nat. Lena Fanter, Dipl.-Ges.oec. Julia Knierim   +2 more
doaj   +1 more source

Relevance of indirect comparisons in the German early benefit assessment and in comparison to HTA processes in England, France and Scotland [PDF]

, 2014
Early benefit assessment in Germany under the legislative framework of AMNOG (Arzneimittelmarktneuordnungsgesetz) requires direct comparisons of the new drug with appropriate comparators determined by the Federal Joint Committee (G-BA).
Dippel, Franz-Werner, Gasche, David, Lebioda, Andrea, Plantör, Stefan, Theobald, Karlheinz   +4 more
core   +3 more sources

Targeted antenatal anti-D prophylaxis for RhD-negative pregnant women: a systematic review

BMC Pregnancy and Childbirth, 2020
Background All non-sensitized Rhesus D (RhD)-negative pregnant women in Germany receive antenatal anti-D prophylaxis without knowledge of fetal RhD status.
Britta Runkel, Gregor Bein, Wiebke Sieben, Dorothea Sow, Stephanie Polus, Daniel Fleer   +5 more
doaj   +1 more source

A systematic comparison of different composite measures (DAS 28, CDAI, SDAI, and Boolean approach) for determining treatment effects on low disease activity and remission in rheumatoid arthritis

BMC Rheumatology, 2022
Background Some composite measures for determining the treatment effects of disease-modifying antirheumatic drugs on remission and low disease activity (LDA) in rheumatoid arthritis (RA) may produce misleading results if they include an acute phase ...
Kirsten Janke, Corinna Kiefer, Natalie McGauran, Bernd Richter, Dietmar Krause, Beate Wieseler   +5 more
doaj   +1 more source

Integrating patients' views into health technology assessment: Analytic hierarchy process (AHP) as a method to elicit patient preferences [PDF]

, 2011
Background: Patient involvement is widely acknowledged to be a valuable component in health technology assessment (HTA) and healthcare decision making.
Bastian, Hilda, Danner, Marion, Dintsios, Charalabos-Markos, Gerber, Andreas, Hummel, Marjan J., IJzerman, Maarten J., Manen, Jeannette G. van, Volz, Fabian, Wiegard, Beate   +8 more
core   +4 more sources

Untersuchung von Methoden zur Überprüfbarkeit von Ergebnissen von Studienpopulationen auf Teilpopulationen

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2018
Background: When assessing the benefit of an intervention, the study population (SP) may consist of a relevant target population (ZP) and a non-relevant population (nZP).
Beckmann, Lars, Grouven, Ulrich, Kieser, Meinhard, Sieben, Wiebke, Skipka, Guido, Bender, Ralf   +5 more
doaj   +1 more source

The Draft Report by the Institute for Quality and Efficiency in Healthcare Does Not Provide Any Evidence That Graded Exercise Therapy and Cognitive Behavioral Therapy Are Safe and Effective Treatments for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Diseases, 2023
The German Institute for Quality and Efficiency in Healthcare (IQWiG) recently published its draft report to the government about myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Mark Vink, Alexandra Vink-Niese
doaj   +1 more source

Prioritisation in medicine – discussion of a reality [PDF]

, 2012
Welche gesellschaftlichen Zwänge wirken auf die Medizin und ihre Anwender ein? Wie ist das Verhältnis von Ökonomie und medizinisch Gebotenem? Wie steht es mit der Finanzierung der nicht evidenzbasierten Behandlung?
Finke, Ulrich, Hoffmann, Gerd
core   +1 more source