Results 81 to 90 of about 5,242 (246)
The Politics of Evidence Use in Health Policy Making in Germany-the Case of Regulating Hospital Minimum Volumes. [PDF]
, 2017 This article examines the role of scientific evidence in informing health policy decisions in Germany, using minimum volumes policy as a case study. It argues that scientific evidence was used strategically at various stages of the policy process both by
Ettelt, S
core +3 more sources
Subthalamic Deep Brain Stimulation: Mapping Non‐Motor Outcomes to Structural Connections
Human Brain Mapping, Volume 46, Issue 5, 01 April 2025.Delivering stimulation to the correct target is a challenge for deep brain stimulation. We propose a new approach that allows condensing a large battery of scores onto a few main dimensions, identifying the structural connections associated with each dimension, and estimating changes in individual scores based on their stimulation.
Garance M. Meyer +12 more
wiley +1 more source
Time to review the role of surrogate endpoints in health policy: state of the art and the way forward [PDF]
, 2017 The efficacy of medicines, medical devices, and other health technologies should be proved in trials that assess final patient-relevant outcomes such as survival or morbidity.
Buyse, M. +5 more
core +2 more sources
Biometrical Journal, Volume 67, Issue 1, February 2025.ABSTRACT In a longitudinal clinical registry, different measurement instruments might have been used for assessing individuals at different time points. To combine them, we investigate deep learning techniques for obtaining a joint latent representation, to which the items of different measurement instruments are mapped.
Maren Hackenberg +5 more
wiley +1 more source
Monitor VersorgungsforschungDer Gesetzgeber hat mit dem 2019 eingeführten Instrument der anwendungsbegleitenden Datenerhebung (AbD) die Möglichkeit geschaffen, vergleichende Daten in der laufenden Versorgung zu erheben.
Dr. rer. nat. Matthias Wilken +1 more
doaj +1 more source
Systematic review on inhaled corticosteroid monotherapy and its efficacy and safety in longterm treatment of patients with chronic obstructive pulmonary disease (COPD) [PDF]
--chronic obstructive pulmonary disease,COPD,corticosteroids,systematic review,chronisch obstruktive Lungenerkrankung,COPD,Kortikosteroid,systematischer ...
Buchberger, Barbara +4 more
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European Journal of Haematology, Volume 113, Issue 3, Page 371-383, September 2024.Abstract Objectives Novel interventions (axicabtagene ciloleucel [axi‐cel], lisocabtagene maraleucel [liso‐cel], tafasitamab‐lenalidomide [Tafa‐L], polatuzumab‐rituximab‐bendamustine [pola‐BR]) improve clinical outcomes in second‐line (2 L) treatment of transplant‐ineligible patients with early relapse or refractory (R/R) diffuse large B cell lymphoma (
Melina Sophie Kurte +7 more
wiley +1 more source
Systematic Reviews, 2017 Background The number of systematic reviews of economic evaluations is steadily increasing. This is probably related to the continuing pressure on health budgets worldwide which makes an efficient resource allocation increasingly crucial.
Miriam Luhnen +3 more
doaj +1 more source
Challenges and methodologies in using progression free survival as a surrogate for overall survival In oncology [PDF]
, 2018 Objectives: A primary outcome in oncology trials is overall survival (OS). However, to estimate OS accurately requires a sufficient number of patients to have died, which may take a long time. If an alternative end point is sufficiently highly correlated
Fischer, A. +2 more
core +1 more source
Systematic Reviews, 2017 Background Overviews of systematic reviews (overviews) attempt to systematically retrieve and summarize the results of multiple systematic reviews (SRs) for a given condition or public health problem.
Dawid Pieper +4 more
doaj +1 more source