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Leptin attenuates heat stress-induced mitoxyperilysis in porcine Sertoli cells by suppressing the mtDNA-cGAS-STING axis. [PDF]

J Anim Sci Biotechnol
Guo M, Zhang J, Gu S, Gao Y, Zhu Z, Zhang T, Lu H, Luo J, Zeng W.   +8 more
europepmc   +1 more source

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Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3

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Hui Zheng, Renxia Zhang, Xiangjie Chen
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Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection

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Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response

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Shouheng Jin, Yaoxing Wu, Jun Cui
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IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation

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Sonam Popli, Laura E Nagy, Saurabh Chattopadhyay   +2 more
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Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice

Proceedings of the National Academy of Sciences of the United States of America, 2018
Takaya Abe, Rudolf Grosschedl, Hiroshi Kiyonari   +2 more
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S‐glutathionylation of IRF3 regulates IRF3–CBP interaction and activation of the IFNβ pathway

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Dimitrios Thanos
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Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3

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Ji-ming Feng, Zhengfan Jiang, XiaoJun Huang   +2 more
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Seneca Valley Virus 3C abrogates the IRF3- and IRF7-mediated innate immune response by degrading IRF3 and IRF7

Virology, 2018
Haixue Zheng, Zixiang Zhu, Linna Ma
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Induction of INKIT by Viral Infection Negatively Regulates Antiviral Responses through Inhibiting Phosphorylation of p65 and IRF3

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Zan Huang, Hai-Ning Du, Bo Zhong
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