Results 41 to 50 of about 59,836 (250)

Affinity-Based Luminescent Iridium(III) Complexes for the Detection of Disease-Related Proteins

Inorganics, 2022
The occurrence of diseases is usually accompanied by changes in protein levels and types. These differentially expressed proteins can be used as biomarkers for the diagnosis and treatment of diseases.
Wanhe Wang, Jianhua Liu, Sang-Cuo Nao, Dik-Lung Ma, Jing Wang, Chung-Hang Leung   +5 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Formation of nanostructured iridium and polycluster diamond films [PDF]

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2007
Iridium films and layered structures "iridium — diamond" were formed on Al2O3, MgO and SrTiO3 substrates. Iridium films were obtained by magnetron sputtering, and polycluster diamond films — by microwave discharge method. Structure of iridium and diamond
Pashchenko P. V., Timofeev M. A., Mitin V. S., Dzbanovskiy N. N., Suetin N. V., Samoylovich M. I., Pal' A. F., Belyanin A. F.   +7 more
doaj   +2 more sources

Quantifying manual editing time in autocontouring via audit log analysis

Physics and Imaging in Radiation Oncology
Background and purpose: Artificial intelligence (AI)-based contouring reduces delineation workload, yet manual corrections remain required. Reliable, scalable quantification of structure-level editing time is needed to evaluate clinical usability beyond ...
Geert De Kerf, Gabriele Balletti, Nina Menten, Michaël Claessens, Thibaut D'homme, Joachim Marichal, Mark J. Gooding, Dirk Verellen   +7 more
doaj   +1 more source

Study of Iridium electrodeposition on Ti and A304

International Journal of Electrochemical Science, 2015
Iridium is considered a valuable material due to its physical, chemical and electrocatalytic properties [1-3]. Iridium recovery from post-consumed industrial materials and effluents [4, 5] is necessary, since the natural resources for its production are ...
S.S. Serrano Lopez, V.E. Reyes Cruz, J.A. Cobos-Murcia, M.A. Veloz Rodríguez, J. Hernandez Avila   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A Panchromatic Cyclometalated Iridium Dye Based on 2-Thienyl-Perimidine

Molecules, 2022
Though 2-arylperimidines have never been used in iridium(III) chemistry, the present study on structural, electronic and optical properties of N-unsubstituted and N-methylated 2-(2-thienyl)perimidines, supported by DFT/TDDFT calculations, has shown that ...
Paulina Kalle, Marina A. Kiseleva, Sergei V. Tatarin, Daniil E. Smirnov, Alexander Y. Zakharov, Viktor V. Emets, Andrei V. Churakov, Stanislav I. Bezzubov   +7 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Automated evaluation of organ sparing in prostate stereotactic body radiation therapy using dose-gradient metrics

Physics and Imaging in Radiation Oncology
Background and purpose: Traditional dose-volume histogram (DVH) metrics used in radiotherapy plan evaluation lack spatial information and are sensitive to organ volume variations. This study investigated the use of Dose Gradient Curves (DGCs) as a robust,
Geert De Kerf, Michaël Claessens, Thibaut D’homme, Piet Dirix, Piet Ost, Dirk Verellen   +5 more
doaj   +1 more source