Study of chiral iridium N,P ligand complexes as catalysts for the asymmetric hydrogenation of different substrate classes [PDF]
, 2014 The objective of this thesis was the synthesis and further development of different iridium N,P ligand complexes as well as the evaluation and application of different challenging substrate classes in the asymmetric hydrogenation using iridium-based ...
Müller, Marc-André
core +1 more source
Iridium-catalyzed asymmetric hydrogenation of furan derivatives and thiophene 1,1-dioxides [PDF]
, 2014 The main focus of the research presented in this dissertation was to broaden the substrate scope of the iridium-catalyzed asymmetric hydrogenation of heterocyclic compounds.
Pauli, Larissa
core +1 more source
Iridium-Catalyzed Reductive Nucleophilic Addition to Secondary Amides [PDF]
, 2018 An iridium-catalyzed reductive nucleophilic addition to secondary amides is reported. After the iridium-catalyzed reduction, the resulting imines can undergo the Strecker reaction, the Mannich reaction, allylation, and [3 + 2]-cycloaddition.
Yoshito Takahashi (4675366) +7 more
core +1 more source
Iridium-Catalyzed Cyclization of Isoxazolines and Alkenes: Divergent Access to Pyrrolidines, Pyrroles, and Carbazoles [PDF]
, 2016 A heterogeneous iridium-complex-catalyzed N–O-cleaving rearrangement/cyclization of 2,3-dihydroisoxazoles with alkenes has been developed. It provides divergent access to multiple substituted pyrrolidines, pyrroles, and carbazoles.
Zu-Feng Xiao (1457725) +5 more
core +1 more source
Iridium-Catalyzed Asymmetric Allylic Amination Reactions with N‑Aryl Phosphoramidite Ligands [PDF]
, 2016 A series of N-aryl phosphoramidite ligands were synthesized, and the iridium complexes derived from these novel ligands were proven to be efficient catalysts for asymmetric intermolecular allylic amination reactions. This C–N bond forming process readily
Xiao Zhang (152326) +3 more
core +1 more source
Iridium-Catalyzed Asymmetric Transfer Hydrogenation of Alkynyl Ketones Using Sodium Formate and Ethanol as Hydrogen Sources [PDF]
, 2018 A green and efficient iridium-catalyzed asymmetric transfer hydrogenation of alkynyl ketones to chiral propargylic alcohols has been developed. By using sodium formate and ethanol as hydrogen sources, a series of alkynyl ketones were hydrogenated by ...
Jian-Hua Xie +9 more
core +1 more source
Organometallic half-sandwich iridium anticancer complexes [PDF]
, 2011 The low-spin 5d6 IrIII organometallic half-sandwich complexes [(η5-Cpx)Ir(XY)Cl]0/+, Cpx = Cp*, tetramethyl(phenyl)cyclopentadienyl (Cpxph), or tetramethyl(biphenyl)cyclopentadienyl (Cpxbiph), XY = 1,10-phenanthroline (4−6), 2,2′-bipyridine (7−9 ...
Liu, Zhe +34 more
core +1 more source
Iridium-Catalyzed [5 + 1] Cycloaddition: Allenylcyclopropane as a Five-Carbon Assembling Unit [PDF]
, 2016 Iridium-Catalyzed [5 + 1] Cycloaddition: Allenylcyclopropane as a Five-Carbon Assembling ...
Itaru Tsuji (3042756) +4 more
core +1 more source
Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source
Iridium-Catalyzed Intramolecular β‑C–H Alkenylation of Ketones with Alkynes via a Hydride-Transfer Approach [PDF]
, 2022 Direct functionalization of carbonyl β C–H bonds without using directing groups has not been a trivial task, and it is even more challenging to realize the corresponding atom-economical transformations with common alkenes or alkynes as the coupling ...
Bo Zhou (15092) +4 more
core +1 more source