Results 1 to 10 of about 18,396 (251)

Effects of 5-azaC on Iridoid Glycoside Accumulation and DNA Methylation in Rehmannia glutinosa

open access: yesFrontiers in Plant Science, 2022
Iridoid glycoside is the important secondary metabolite and the main active component in Rehmannia glutinosa. However, the mechanisms that underlie the regulation of iridoid glycoside biosynthesis remain poorly understood in R. glutinosa.
Tianyu Dong   +12 more
doaj   +2 more sources

Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis

open access: yesScientific Reports, 2022
Eucommia ulmoides Oliver is one of the commonly used traditional Chinese medicines for the treatment of osteoporosis, and iridoid glycosides are considered to be its active ingredients against osteoporosis.
Ting Wang   +8 more
doaj   +2 more sources

BHLH IRIDOID SYNTHESIS 3 is a member of a bHLH gene cluster regulating terpenoid indole alkaloid biosynthesis in Catharanthus roseus

open access: yesPlant Direct, 2021
Basic helix‐loop‐helix (bHLH) transcription factors (TFs) are key regulators of plant specialized metabolites, including terpenoid indole alkaloids (TIAs) in Catharanthus roseus.
Sanjay Kumar Singh   +5 more
doaj   +2 more sources

New Iridoid Derivatives from the Fruits of Cornus officinalis and Their Neuroprotective Activities

open access: yesMolecules, 2019
Three previously undescribed iridoids, cornusfurals A⁻C, were isolated from the ethanolic extracts of fruits of Cornus officinalis. Their structures were elucidated by spectroscopic methods, including one-dimensional and two-dimensional nuclear ...
Lin-lin Ji   +6 more
doaj   +2 more sources

Studies of the structure-antioxidant activity relationships and antioxidant activity mechanism of iridoid valepotriates and their degradation products. [PDF]

open access: yesPLoS ONE, 2017
Oxidative stress has been associated with diverse diseases, including obesity, cancer and neurodegeneration. In fact, Valeriana jatamansi Jones (valerian) and its extracts possess strong antioxidant activities that extend their application in clinical ...
Feifei Wang   +6 more
doaj   +2 more sources

Analysis of the Rehmannia chingii genome identifies RcCYP72H7 as an epoxidase in iridoid glycoside biosynthesis

open access: yesNature Communications
Rehmannia chingii (2n = 2x = 28) is an important folk medicinal plant with high therapeutic value, particularly due to its richness in iridoid glycosides. However, research on its evolution and gene functional identification has been hindered by the lack
Fengqing Wang   +16 more
doaj   +2 more sources

Functional iridoid synthases from iridoid producing and non-producing Nepeta species (subfam. Nepetoidae, fam. Lamiaceae)

open access: yesFrontiers in Plant Science
Iridoids, a class of atypical monoterpenes, exhibit exceptional diversity within the Nepeta genus (subfam. Nepetoidae, fam. Lamiaceae).The majority of these plants produce iridoids of the unique stereochemistry, with nepetalactones (NLs) predominating ...
Neda Aničić   +11 more
doaj   +2 more sources

Quality Evaluation and Antioxidant Activity of Cultivated Gentiana siphonantha: An Ethnic Medicine from the Tibetan Plateau [PDF]

open access: yesMolecules
Gentiana species are widely used in traditional and modern medicine, and Gentiana siphonantha is an important medicinal representative. To evaluate the quality characteristics of cultivated G.
Jiamin Li   +5 more
doaj   +2 more sources

Differential iridoid production as revealed by a diversity panel of 84 cultivated and wild blueberry species.

open access: yesPLoS ONE, 2017
Cultivated blueberry (Vaccinium corymbosum, Vaccinium angustifolium, Vaccinium darrowii, and Vaccinium virgatum) is an economically important fruit crop native to North America and a member of the Ericaceae family. Several species in the Ericaceae family
Courtney P Leisner   +4 more
doaj   +2 more sources

Iridoids from Traditional Chinese Medicine for Neuropathic Pain: Therapeutic Potential and Molecular Mechanisms [PDF]

open access: yesDrug Design, Development and Therapy
Wenjun Wang,1,2 Tianlong Liu,3 Yi Ding,4 Xiaolong Liu,1 Ren Qingji,5 Yi Zhang,6 Zhengxiang Zhang1 1Yan’an Medical College, Yan’an University, Yan’an, Shaanxi, People’s Republic of China; 2Department of Traditional Chinese Medicine, Tangdu Hospital ...
Wang W   +6 more
doaj   +2 more sources

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