Results 1 to 10 of about 13,958 (226)

The Hedyotis diffusa chromosome-level genome and multi-omics analysis provide new insights into the iridoids biosynthetic pathway [PDF]

Frontiers in Plant Science
IntroductionHedyotis diffusa (Rubiaceae) is a medicinal herb with significant therapeutic potential, primarily attributed to its bioactive iridoid compounds.
Pengyu Chen, Pengyu Chen, Zhuang Huang, Zhuang Huang, Mingzhu Yin, Yu-xin Wen, Yu-xin Wen, Qi Jiang, Qi Jiang, Ping Huang, Rui Qian, Rui Qian, Xing Hong, Xing Hong, Kaojiang Zhu, Kaojiang Zhu, Benjiang Xiao, Benjiang Xiao, Meng Chen, Meng Chen, Shihao Li, Shihao Li, Fang Huang, Lin-tao Han, Lin-tao Han   +24 more
doaj   +2 more sources

Quality Evaluation and Antioxidant Activity of Cultivated Gentiana siphonantha: An Ethnic Medicine from the Tibetan Plateau [PDF]

Molecules
Gentiana species are widely used in traditional and modern medicine, and Gentiana siphonantha is an important medicinal representative. To evaluate the quality characteristics of cultivated G.
Jiamin Li, Liyan Zang, Xiaoming Song, Zixuan Liu, Hongmei Li, Jing Sun   +5 more
doaj   +2 more sources

Iridoids from Traditional Chinese Medicine for Neuropathic Pain: Therapeutic Potential and Molecular Mechanisms [PDF]

Drug Design, Development and Therapy
Wenjun Wang,1,2 Tianlong Liu,3 Yi Ding,4 Xiaolong Liu,1 Ren Qingji,5 Yi Zhang,6 Zhengxiang Zhang1 1Yan’an Medical College, Yan’an University, Yan’an, Shaanxi, People’s Republic of China; 2Department of Traditional Chinese Medicine, Tangdu Hospital ...
Wang W, Liu T, Ding Y, Liu X, Qingji R, Zhang Y, Zhang Z   +6 more
doaj   +2 more sources

Analysis of the Rehmannia chingii genome identifies RcCYP72H7 as an epoxidase in iridoid glycoside biosynthesis [PDF]

Nature Communications
Rehmannia chingii (2n = 2x = 28) is an important folk medicinal plant with high therapeutic value, particularly due to its richness in iridoid glycosides. However, research on its evolution and gene functional identification has been hindered by the lack
Fengqing Wang, Zhennan Jiang, Junge Gao, Chunyan Miao, Ci Song, Yahe Yang, Ning Ding, Yajing Li, Hongzheng Sun, Caixia Xie, Bao Zhang, Pengyu Zhang, Li Gu, Qiuwen Hao, Zhongyi Zhang, Luqi Huang, Yuan Yuan   +16 more
doaj   +2 more sources

Prolonged Administration of Rudgea viburnoides (Cham.) Benth. Prevents Impairment of Redox Status, Renal Dysfunction, and Cardiovascular Damage in 2K1C-Hypertensive Rats by Inhibiting ACE Activity and NO-GMPC Pathway Activation

Pharmaceutics, 2021
Rudgea viburnoides is widely found in the Brazilian Cerrado, and commonly used in Brazilian folk medicine. In this study, we evaluated the effects of prolonged administration of the aqueous extract from R.
Fernanda Viana Paulin, Rhanany Alan Calloi Palozi, Bethânia Rosa Lorençone, Arthur Ladeira Macedo, Lucas Pires Guarnier, Cleide Adriane Signor Tirloni, Paulo Vitor Moreira Romão, Arquimedes Gasparotto Junior, Denise Brentan Silva   +8 more
doaj   +1 more source

Effects of 5-azaC on Iridoid Glycoside Accumulation and DNA Methylation in Rehmannia glutinosa

Frontiers in Plant Science, 2022
Iridoid glycoside is the important secondary metabolite and the main active component in Rehmannia glutinosa. However, the mechanisms that underlie the regulation of iridoid glycoside biosynthesis remain poorly understood in R. glutinosa.
Tianyu Dong, Tianyu Dong, Shanglin Song, Ying Wang, Ruixue Yang, Peilei Chen, Peilei Chen, Jiuchang Su, Jiuchang Su, Xinru Ding, Yongkang Liu, Hongying Duan, Hongying Duan   +12 more
doaj   +1 more source

Identification of Small-Molecule Bioactive Constituents from the Leaves of Vaccinium bracteatum Confirms It as a Potential Functional Food with Health Benefits

Foods, 2023
The health benefits of Vaccinium bracteatum are well recorded in ancient Chinese medical books and were also demonstrated by modern researches. However, the relationship between its beneficial functions and specific chemical constituents has not been ...
Yin-Yin Wang, Jun-Sheng Zhang, Xin-Xin Wang, Lin-Lin Tian, Yu-Peng Li, Chao Wang, Ren-Fen Ma, Yi-Ke Yin, Jie Bao, Hua Zhang   +9 more
doaj   +1 more source

Genome-Wide Differential Methylation Profiles from Two Terpene-Rich Medicinal Plant Extracts Administered in Osteoarthritis Rats

Plants, 2021
Extracts from the plants Phlomis umbrosa and Dipsacus asperoides—which are widely used in Korean and Chinese traditional medicine to treat osteoarthritis and other bone diseases—were used to treat experimental osteoarthritis (OA) rats.
Younhee Shin, Sathiyamoorthy Subramaniyam, Jin-Mi Chun, Ji-Hyeon Jeon, Ji-Man Hong, Hojin Jung, Boseok Seong, Chul Kim   +7 more
doaj   +1 more source

Nyctanthes arbor-tristis L.: Perspective of phytochemical-based inhibition of fatty acid biosynthesis in Mycobacterium tuberculosis

International Journal of Plant Based Pharmaceuticals, 2022
Nyctanthes arbor-tristis L. contains various phytochemicals with tremendous potential to fight against different infections. However, the effect of these phytochemicals on Mycobacterium tuberculosis is yet unknown. Treatment of multi-drug resistance (MDR)
Subendu Sarkar, Rajender Pal Singh
doaj   +1 more source

Characteristics, Isolation Methods, and Biological Properties of Aucubin

Molecules, 2023
Aucubin is an iridoid glycoside widely spread in the families Cornaceae, Garryaceae, Orobanchaceae, Globulariaceae, Eucommiaceae, Scrophulariaceae, Plantaginaceae, and Rubiaceae.
Kartini Kartini, Michelle Abigail Irawan, Finna Setiawan, Nikmatul Ikhrom Eka Jayani   +3 more
doaj   +1 more source