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Nine Unique Iridoids and Iridoid Glycosides From Patrinia scabiosaefolia [PDF]

open access: yesFrontiers in Chemistry, 2021
Patrinia scabiosaefolia is a medical and edible Chinese herb with high nutritional and medicinal value. The continuing study of its chemical constituents led to the discovery of nine unique iridoids and iridoid glycosides, including three new iridoids (1-
Zhenhua Liu   +16 more
doaj   +6 more sources

Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis [PDF]

open access: yesScientific Reports, 2022
Eucommia ulmoides Oliver is one of the commonly used traditional Chinese medicines for the treatment of osteoporosis, and iridoid glycosides are considered to be its active ingredients against osteoporosis.
Ting Wang   +8 more
doaj   +3 more sources

The Potential Protective Effect of Iridoid Glycosides Isolated From Osmanthus fragrans Seeds Against the Development of Immune Liver Injury in Mice [PDF]

open access: yesFrontiers in Pharmacology, 2021
Objective: The iridoid glycosides were extracted and separated from Osmanthus fragrans seeds, and the potential protective effect of Osmanthus fragrans seed extract on concanavalin A-induced immune liver injury in mice was studied.Methods:Osmanthus ...
Yuchen Zhang   +10 more
doaj   +3 more sources

Inhibition of GSK_3β by Iridoid Glycosides of Snowberry (Symphoricarpos albus) Effective in the Treatment of Alzheimer’s Disease Using Computational Drug Design Methods [PDF]

open access: yesFrontiers in Chemistry, 2021
The inhibition of glycogen synthase kinase-3β (GSK-3β) activity prevents tau hyperphosphorylation and binds it to the microtubule network. Therefore, a GSK-3β inhibitor may be a recommended drug for Alzheimer’s treatment.
Marzieh Eskandarzadeh   +6 more
doaj   +3 more sources

Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of Lasianthus verticillatus (Lour.) Merr. [PDF]

open access: yesMolecules, 2020
A series of iridoid glycosides were isolated from the leaves of Lasianthus verticillatus (Lour.) Merr., belonging to family Rubiaceae. A new iridoid glycoside, lasianoside F (1), and three new bis-iridoid glycosides, lasianosides G–I (2–4), together with
Gadah Abdulaziz Al-Hamoud   +9 more
doaj   +3 more sources

Distribution profile of iridoid glycosides and phenolic compounds in two Barleria species and their correlation with antioxidant and antibacterial activity [PDF]

open access: yesFrontiers in Plant Science, 2023
IntroductionBarleria prionitis is known for its medicinal properties from ancient times. Bioactive iridoid glycosides and phenolic compounds have been isolated from leaves of this plant.
Shachi Singh   +4 more
doaj   +2 more sources

The Urate-Lowering Effects and Renal Protective Activity of Iridoid Glycosides from Paederia foetida in Rats with Hyperuricemia-Induced Kidney Injury: A Pharmacological and Molecular Docking Study [PDF]

open access: yesMolecules
(1) Background: The urate-lowering effects of three iridoid glycosides, which are paederosidic acid, paederosidic acid methyl ester, and paederoside, isolated from Paederia foetida and the protection they provide against hyperuricemia-induced kidney ...
Haifeng Zhou   +5 more
doaj   +2 more sources

Lipid Nanoparticles Loaded with Iridoid Glycosides: Development and Optimization Using Experimental Factorial Design [PDF]

open access: yesMolecules, 2021
Lipid nanoparticles based on multiple emulsion (W/O/W) systems are suitable for incorporating hydrophilic active substances, including iridoid glycosides.
Marta Dąbrowska   +2 more
doaj   +2 more sources

Bis-Iridoid Glycosides and Triterpenoids from Kolkwitzia amabilis and Their Potential as Inhibitors of ACC1 and ACL [PDF]

open access: yesMolecules
A comprehensive phytochemical investigation of the twigs/leaves and flower buds of Kolkwitzia amabilis, a rare deciduous shrub native to China, led to the isolation of 39 structurally diverse compounds.
Jiang Wan   +8 more
doaj   +2 more sources

Iridoids from Traditional Chinese Medicine for Neuropathic Pain: Therapeutic Potential and Molecular Mechanisms [PDF]

open access: yesDrug Design, Development and Therapy
Wenjun Wang,1,2 Tianlong Liu,3 Yi Ding,4 Xiaolong Liu,1 Ren Qingji,5 Yi Zhang,6 Zhengxiang Zhang1 1Yan’an Medical College, Yan’an University, Yan’an, Shaanxi, People’s Republic of China; 2Department of Traditional Chinese Medicine, Tangdu Hospital ...
Wang W   +6 more
doaj   +2 more sources

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