Inhibition of GSK_3β by Iridoid Glycosides of Snowberry (Symphoricarpos albus) Effective in the Treatment of Alzheimer’s Disease Using Computational Drug Design Methods [PDF]
The inhibition of glycogen synthase kinase-3β (GSK-3β) activity prevents tau hyperphosphorylation and binds it to the microtubule network. Therefore, a GSK-3β inhibitor may be a recommended drug for Alzheimer’s treatment.
Marzieh Eskandarzadeh +6 more
doaj +2 more sources
Callitriche cophocarpa as a biotechnological resource: optimizing in vitro cultures and elicitation to boost biologically active phenolic acids and phenylethanoid and iridoid glycosides [PDF]
Background Callitriche cophocarpa Sendtn. (water starwort; Plantaginaceae) is an aquatic higher plant common in natural environments worldwide. The plant is used in folk medicine due to its ability to synthesize large amounts of secondary metabolites ...
Wojciech Makowski +11 more
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Bis-Iridoid Glycosides and Triterpenoids from Kolkwitzia amabilis and Their Potential as Inhibitors of ACC1 and ACL [PDF]
A comprehensive phytochemical investigation of the twigs/leaves and flower buds of Kolkwitzia amabilis, a rare deciduous shrub native to China, led to the isolation of 39 structurally diverse compounds.
Jiang Wan +8 more
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Iridoids from Traditional Chinese Medicine for Neuropathic Pain: Therapeutic Potential and Molecular Mechanisms [PDF]
Wenjun Wang,1,2 Tianlong Liu,3 Yi Ding,4 Xiaolong Liu,1 Ren Qingji,5 Yi Zhang,6 Zhengxiang Zhang1 1Yan’an Medical College, Yan’an University, Yan’an, Shaanxi, People’s Republic of China; 2Department of Traditional Chinese Medicine, Tangdu Hospital ...
Wang W +6 more
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Quality Evaluation and Antioxidant Activity of Cultivated Gentiana siphonantha: An Ethnic Medicine from the Tibetan Plateau [PDF]
Gentiana species are widely used in traditional and modern medicine, and Gentiana siphonantha is an important medicinal representative. To evaluate the quality characteristics of cultivated G.
Jiamin Li +5 more
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Phenylethanoid and Iridoid Glycosides from Veronica persica.
AbstractFor Abstract see ChemInform Abstract in Full Text.
Saracoglu, I +3 more
openaire +5 more sources
Fresh Rehmanniae Radix, as well as its processed products, are widely used in the clinical practice of traditional Chinese medicine. It is mainly available in four forms: fresh Rehmanniae Radix, raw Rehmanniae Radix, prepared Rehmanniae Radix, and nine ...
Lu Xu +4 more
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Antiviral iridoid glycosides from Clerodendrum myricoides
NMR data (FID, mnova) and ...
Umereweneza, Daniel +8 more
openaire +4 more sources
Medicinal plants play an important role in traditional medicine and new drug development, but the increased use of wild plant-based traditional medicine presents a potential biodiversity conservation threat.
Ji Zhang +4 more
doaj +1 more source
Microorganisms and nematodes increase levels of secondary metabolites in roots and root exudates of Plantago lanceolata [PDF]
Plant secondary metabolites play an important role in constitutive and inducible direct defense of plants against their natural enemies. While induction of defense by aboveground pathogens and herbivores is well-studied, induction by belowground ...
Wurst, S. +8 more
core +2 more sources

