The Urate-Lowering Effects and Renal Protective Activity of Iridoid Glycosides from Paederia foetida in Rats with Hyperuricemia-Induced Kidney Injury: A Pharmacological and Molecular Docking Study [PDF]
Molecules(1) Background: The urate-lowering effects of three iridoid glycosides, which are paederosidic acid, paederosidic acid methyl ester, and paederoside, isolated from Paederia foetida and the protection they provide against hyperuricemia-induced kidney ...
Haifeng Zhou +5 more
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The Potential Protective Effect of Iridoid Glycosides Isolated From Osmanthus fragrans Seeds Against the Development of Immune Liver Injury in Mice [PDF]
Frontiers in Pharmacology, 2021 Objective: The iridoid glycosides were extracted and separated from Osmanthus fragrans seeds, and the potential protective effect of Osmanthus fragrans seed extract on concanavalin A-induced immune liver injury in mice was studied.Methods:Osmanthus ...
Yuchen Zhang +10 more
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Lipid Nanoparticles Loaded with Iridoid Glycosides: Development and Optimization Using Experimental Factorial Design [PDF]
Molecules, 2021 Lipid nanoparticles based on multiple emulsion (W/O/W) systems are suitable for incorporating hydrophilic active substances, including iridoid glycosides.
Marta Dąbrowska +2 more
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Potential Roles of Iridoid Glycosides and Their Underlying Mechanisms against Diverse Cancer Growth and Metastasis: Do They Have an Inhibitory Effect on Cancer Progression? [PDF]
Nutrients, 2021 Iridoids are glycosides found in plants, having inherent roles in defending them against infection by viruses and microorganisms, and in the rapid repair of damaged areas.
Cho-Won Kim, Kyung-Chul Choi
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Inhibition of GSK_3β by Iridoid Glycosides of Snowberry (Symphoricarpos albus) Effective in the Treatment of Alzheimer’s Disease Using Computational Drug Design Methods [PDF]
Frontiers in Chemistry, 2021 The inhibition of glycogen synthase kinase-3β (GSK-3β) activity prevents tau hyperphosphorylation and binds it to the microtubule network. Therefore, a GSK-3β inhibitor may be a recommended drug for Alzheimer’s treatment.
Marzieh Eskandarzadeh +6 more
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Bis-Iridoid Glycosides and Triterpenoids from Kolkwitzia amabilis and Their Potential as Inhibitors of ACC1 and ACL [PDF]
MoleculesA comprehensive phytochemical investigation of the twigs/leaves and flower buds of Kolkwitzia amabilis, a rare deciduous shrub native to China, led to the isolation of 39 structurally diverse compounds.
Jiang Wan +8 more
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Callitriche cophocarpa as a biotechnological resource: optimizing in vitro cultures and elicitation to boost biologically active phenolic acids and phenylethanoid and iridoid glycosides [PDF]
BMC Plant BiologyBackground Callitriche cophocarpa Sendtn. (water starwort; Plantaginaceae) is an aquatic higher plant common in natural environments worldwide. The plant is used in folk medicine due to its ability to synthesize large amounts of secondary metabolites ...
Wojciech Makowski +11 more
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Phenylethanoid and Iridoid Glycosides from Veronica persica. [PDF]
ChemInform, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
Harput, U. Sebnem +3 more
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Quality Evaluation and Antioxidant Activity of Cultivated Gentiana siphonantha: An Ethnic Medicine from the Tibetan Plateau [PDF]
MoleculesGentiana species are widely used in traditional and modern medicine, and Gentiana siphonantha is an important medicinal representative. To evaluate the quality characteristics of cultivated G.
Jiamin Li +5 more
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Iridoids from Traditional Chinese Medicine for Neuropathic Pain: Therapeutic Potential and Molecular Mechanisms [PDF]
Drug Design, Development and TherapyWenjun Wang,1,2 Tianlong Liu,3 Yi Ding,4 Xiaolong Liu,1 Ren Qingji,5 Yi Zhang,6 Zhengxiang Zhang1 1Yan’an Medical College, Yan’an University, Yan’an, Shaanxi, People’s Republic of China; 2Department of Traditional Chinese Medicine, Tangdu Hospital ...
Wang W +6 more
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