Results 41 to 50 of about 6,774 (178)

Integrated Metabolomics and Selection Signal Analysis Provide Insights Into the Selection for Flavonol Biosynthesis Associated With Lettuce Quality Improvement

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lettuce is a critical leafy vegetable consumed worldwide and is a substantial dietary source of health‐promoting compounds. Exploring changes in metabolism during lettuce domestication under artificial selection conditions is important to facilitate further breeding and cultivation for quality improvement.
Xiao Yang, Shiwei Wei, Ge Jin, Li Zhang, Ran Du, Yajun Wang, Chengcheng Shen, Tao Huang, Guotao Huo, Jie Peng, Bo Song, Fangyuan Zhang, Victor Hugo Escalona Contreras, Lijun Luo, Yuejian Li, Francisco A. Tomas‐Barberan, Bin Liu, Qichang Yang   +17 more
wiley   +1 more source

Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of Lasianthus verticillatus (Lour.) Merr.

Molecules, 2020
A series of iridoid glycosides were isolated from the leaves of Lasianthus verticillatus (Lour.) Merr., belonging to family Rubiaceae. A new iridoid glycoside, lasianoside F (1), and three new bis-iridoid glycosides, lasianosides G–I (2–4), together with
Gadah Abdulaziz Al-Hamoud, Raha Saud Orfali, Yoshio Takeda, Sachiko Sugimoto, Yoshi Yamano, Nawal M. Al Musayeib, Omer Ibrahim Fantoukh, Musarat Amina, Hideaki Otsuka, Katsuyoshi Matsunami   +9 more
doaj   +1 more source

Elucidating the Molecular Mechanisms of Vitex negundo L. in Polycystic Ovary Syndrome via Metabolomics‐Driven Network Pharmacology

Biomedical Chromatography, Volume 40, Issue 9, September 2026.
ABSTRACT Polycystic ovary syndrome (PCOS) is a hormonal disorder marked by irregular menstrual cycles, elevated androgen levels, ovarian cysts, hirsutism, acne and other symptoms. While conventional medications such as Metformin and Spironolactone are commonly prescribed, they are often associated with undesirable side effects.
Nishmitha R. Poojary, Neeharika Narisepalli Venkatasai, Kannath U. Sanjay, Supraja M. Kodanch, Padmalatha S. Rai   +4 more
wiley   +1 more source

Biocatalytic routes to stereo-divergent iridoids

Nature Communications, 2022
Iridoid compounds are an important class of natural products. Here, the authors report on the discovery and engineering of nepetalactol-related short chain reductases and their application for the biosynthesis of nepetalactol or nepetalactone ...
Néstor J. Hernández Lozada, Benke Hong, Joshua C. Wood, Lorenzo Caputi, Jérôme Basquin, Ling Chuang, Maritta Kunert, Carlos E. Rodríguez López, Chloe Langley, Dongyan Zhao, C. Robin Buell, Benjamin R. Lichman, Sarah E. O’Connor   +12 more
doaj   +1 more source

Phytochemical Characterization and Bioactive Potential of Stachys germanica L.: LC–MS/MS Profiling and Multi‐Target Biological Activities

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
The 80% ethanolic extract of Stachys germanica L. exhibited a phenolic‐rich phytochemical profile characterized by chlorogenic acid, naringin, luteolin, and kaempferol. The extract demonstrated notable antioxidant capacity, selective tyrosinase and α‐glucosidase inhibition, and significant antibacterial activity against Acinetobacter baumannii ATCC ...
Gözde Gülin İnan, Derya Doğanay, Yiğit İnan, Selin Akyüz‐Çetin, Neşet Neşetoğlu, İbrahim Daniş, Esra Mertoğlu, Durişehvar Özer Ünal, Gokhan Zengin   +8 more
wiley   +1 more source

Morroniside Attenuates Doxorubicin‐Induced Cardiotoxicity by Activating the PI3K/AKT/Nrf2/HO‐1 Pathway to Inhibit Ferroptosis and Oxidative Stress

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Mor activates the PI3K/AKT pathway to promote Nrf2 nuclear translocation and HO‐1 expression, enhancing antioxidants, curbing Fe2+‐induced ROS/lipid peroxidation, suppressing ferroptosis, and alleviating Dox‐induced cardiotoxicity. ABSTRACT Cardiotoxicity induced by doxorubicin (Dox) significantly contributes to increased mortality among cancer ...
Zhi‐Hui Lin, Xing‐Yu Lin, Wen‐Jie Lu, Meng‐Qi Wu, Dong‐Yan Song, Rui‐Dong Cheng   +5 more
wiley   +1 more source

Environmental impact on the variability in quality of Gentiana rigescens, a medicinal plant in southwest China

Global Ecology and Conservation, 2020
Medicinal plants play an important role in traditional medicine and new drug development, but the increased use of wild plant-based traditional medicine presents a potential biodiversity conservation threat.
Ji Zhang, Zhenxian Zhang, Yuanzhong Wang, Yingmei Zuo, Chuantao Cai   +4 more
doaj   +1 more source

Iridoids of fenugreek (Trigonella-foenum-graecum L.) seed extract detected via LC-QTOF-MS analysis

Future Foods, 2021
Fenugreek seed is a traditional medicinal plant with a wide biological activity. In this study, iridoids (Asperulosidic acid (1), 7-O-Methylmorroniside (2), Gentiopicroside (3), Rehmannioside A (4), Loganic acid-6′-O-β-Dglucoside (5), Sweroside (6 ...
Sweeta Akbari, Nour Hamid Abdurahman, Fahim Fayaz, Valantena Noory   +3 more
doaj   +1 more source

Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model

Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski, Victor Schmalle, Luise A. Lauer, Tim Hammerschick, Felix Rüttler, Walter Vetter, Jan Frank, Felipe Jiménez‐Aspee   +7 more
wiley   +1 more source

iridoids

, 2014
Citation: 'iridoids' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.I03253 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source