Long-Term Response and Survival With Liposomal Irinotecan and Fluorouracil in a Patient With Locally Advanced Pancreatic Ductal Adenocarcinoma: A Case Report. [PDF]
Tulyte-Kirzova S +2 more
europepmc +1 more source
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu +8 more
wiley +1 more source
Efficacy and safety of liposomal irinotecan plus nimotuzumab in immune checkpoint inhibitor-refractory recurrent or metastatic nasopharyngeal carcinoma: a single-arm, open-label, phase II trial. [PDF]
He S +10 more
europepmc +1 more source
Nanoparticle‐Mediated Therapy for Glioma: Advances and Prospects
Various nanocarriers, including liposomes, dendrimers, exosomes and gold nanoparticles, are designed to penetrate the blood‐brain barrier and deliver chemotherapy, radiotherapy, immunotherapy, gene therapy, phototherapy, magnetic hyperthermia and sonodynamic therapy for glioma.
Wenqian Jiang +5 more
wiley +1 more source
Impact of prior conventional irinotecan use on nanoliposomal irinotecan efficacy in advanced pancreatic cancer: a meta-analysis. [PDF]
Lee S +7 more
europepmc +1 more source
Capecitabine/irinotecan combination regimens in colorectal cancer.
Capecitabine (Xeloda) and irinotecan (CPT-11, Camptosar) both have demonstrated single-agent activity in patients with colorectal cancer. In an analysis of pooled results of two phase III studies, capecitabine provided advantages over intravenous ...
Kerr, DJ
core
Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley +1 more source
A single-arm phase II trial of <i>UGT1A1</i> genotype-guided high-dose irinotecan rechallenge in refractory metastatic colorectal cancer. [PDF]
Kim H, Hong J, Kong SY, Choi MK.
europepmc +1 more source
This review provides a comprehensive overview of carbon dot–based technologies for breast cancer diagnosis and therapy, including their toxicity profiles. It outlines how C‐dots function as a versatile platform—serving simultaneously as therapeutic agents, drug‐delivery vehicles, and bioimaging tools. The article also highlights cutting‐edge approaches
Srija Sur, Pegah Varamini
wiley +1 more source
Introduction: Cardiotoxicity is an undesirable side effect of chemotherapy that limits the effectiveness of cancer treatment. Almost all cardiotoxic agents cause cardiovascular complications, leading to oxidative stress and other pathological conditions.
Susanna Badalyan +2 more
wiley +1 more source

