Results 121 to 130 of about 79,249 (245)
Cancer Science, EarlyView.This study investigates the role of Sushi domain‐containing 2 (SUSD2) in pancreatic ductal adenocarcinoma (PDAC) and demonstrates that SUSD2 enhances both metastasis and primary tumor growth by promoting integrin β1–FAK signaling. SUSD2 interacts with integrin β1, enhancing adhesion to extracellular matrix (ECM) components such as collagen 1 and ...
Junjiro Yoshida +11 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.Abstract Objectives Stent placement is a standard option for palliative decompression in patients with malignant colorectal obstruction. Long‐term stent placement is associated with perforation, migration, and stent occlusion. Perforation is associated with life expectancy.
Rika Kyo +12 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Barrett's esophageal adenocarcinoma (BEA) with neuroendocrine cell carcinoma (NEC) is a rare disease with a poor prognosis. We report a case of BEA with NEC treated by endoscopic submucosal dissection (ESD) with en bloc resection and long‐term survival was achieved without additional treatment.
Yo Kubota +7 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Recently, zolbetuximab combined with chemotherapy has been approved as a first‐line treatment for advanced gastric cancer (GC). However, to date, no endoscopic images demonstrating endoscopic complete response (eCR) to zolbetuximab plus chemotherapy have been reported.
Akinori Sasaki +6 more
wiley +1 more source
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT A 49‐year‐old male developed liver dysfunction during chemotherapy for rectal cancer located in the rectosigmoid region. Although magnetic resonance cholangiopancreatography initially indicated sclerosing cholangitis, endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed multiple non‐contiguous intraductal ...
Shinji Monoe +5 more
wiley +1 more source
The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.Abstract Recent advancements in antibody‐drug conjugates, including FDA‐approved therapies targeting Nectin‐4 and Trop‐2, have transformed the cancer treatment landscape, including upper tract urothelial carcinoma (UTUC). However, varied treatment effects and drug‐associated adverse effects raise the question of whether patients should be selected ...
Ping Shi +7 more
wiley +1 more source
CPT: Pharmacometrics & Systems PharmacologyPeritoneal metastases (PM) are common in patients with colorectal cancer. Patients with PM have a poor prognosis, and for those who are not eligible for cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC ...
Pascale C. S. Rietveld +9 more
doaj +1 more source
Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?
Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano +13 more
wiley +1 more source
Frontiers in OncologyIntroductionThe aim of this study was to provide a review of the clinical evidence for use of ramucirumab (RAM) plus folinic acid (leucovorin), fluorouracil (5-FU), and irinotecan (FOLFIRI) or irinotecan as second-line treatment in gastroesophageal ...
Haeseong Park +8 more
doaj +1 more source