Results 141 to 150 of about 46,447 (205)

Tumour cell density quantified by artificial intelligence is associated with differential benefit from irinotecan-based chemo-radiotherapy in locally advanced rectal cancer: a post-hoc study of the phase 3 ARISTOTLE trial. [PDF]

EBioMedicine
Shen Z, Brand D, Simard M, West NP, Lopes A, Begum R, Zhang Y, Royle G, Sebag-Montefiore D, Collins Fekete CA, Hawkins MA.   +10 more
europepmc   +1 more source

Irinotecan [PDF]

, 2020
openaire   +1 more source

A Phase II Clinical Trial of Chemotherapy Rechallenge with or without Targeted Therapy in Refractory Metastatic Colorectal Cancer. [PDF]

Oncol Res
Wang C, Huang M, Li W, Sheng X, Zhao X, Zhu X, Chen Z, Zhang Z, Li H, Guo W.   +9 more
europepmc   +1 more source

IGFBP-3 enhances irinotecan efficacy in colorectal cancer <i>via</i> ROS-mediated apoptosis and β-catenin suppression. [PDF]

Res Pharm Sci
Gharehkhani E, Karami M, Bagheri A, Kukandeh MR, Shokrzadeh M.   +4 more
europepmc   +1 more source

Treatment patterns and outcomes of patients with a diagnosis of metastatic pancreatic adenocarcinoma in the United States, 2019-2024. [PDF]

Front Oncol
Fuldeore R, Tan CJ, Kimura T, Farrokhi P, Yang R, Willis C, Asche C, Stenehjem D.   +7 more
europepmc   +1 more source

Single-cell RNA sequencing profiles drug activity within spatially engineered 3D cultures. [PDF]

Nat Commun
King JJ, Mowla A, Kretzmann JA, Bhalla N, Sugianto G, Norret M, Kadolsky UD, Iqbal M, Saxena A, Amos SE, Choi YS, Kennedy BF, Iyer KS, Smith NM, Evans CW.   +14 more
europepmc   +1 more source

A Comprehensive Review on Irinotecan-Induced Delayed Diarrhea: From Mechanisms to Therapeutic Options. [PDF]

Pharmaceuticals (Basel)
Wang Y, Li M, Hu Q, Liu J, Yang Q, Li Q, Zhu X, Dang H, Li H, Wang L, Peng B, Chen Y.   +11 more
europepmc   +1 more source

High therapeutic efficacy of triplet therapy in unresectable or metastatic colorectal cancer and its optimal application strategies. [PDF]

Int J Clin Oncol
Sakuyama H, Okuyama H, Tahara Y, Tsukamoto S, Kita I, Nomura K, Murakami A, Okita Y, Satake H, Kato T, Tsuji A.   +10 more
europepmc   +1 more source

The phase I trial of preoperative short-course chemoradiotherapy with S-1/irinotecan and short-course radiation in locally advanced lower rectal cancer (SHOWTIME study). [PDF]

Radiat Oncol
Kojo K, Tanaka T, Yamanashi T, Miura H, Yokoi K, Kojima K, Yokota K, Kawakami S, Ishiyama H, Yamashita K, Kumamoto Y, Hiki N, Sato T, Naitoh T.   +13 more
europepmc   +1 more source