Results 111 to 120 of about 44,917 (208)

Irinotecan-Loaded Vaterite Microspheres for Drug Delivery: Drug Release and Dissolution Kinetics and Mechanism in an Aqueous Solution and Human Serum. [PDF]

Langmuir
Milner MP, Saint HA, Yang JM, Neumann CCM, Wansch K, Compton RG.   +5 more
europepmc   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Development of an adult whole-body PBPK model of irinotecan and its metabolites for predicting UGT1A1/CYP3A-mediated drug-drug interactions. [PDF]

Front Pharmacol
Chen B, Li L, Xu W, Xu H, Zhu X, He Q, Zhu X, Chi-Lui Ho P, Xiang X, Ji P.   +9 more
europepmc   +1 more source

Dynamics of Circulating Tumor DNA (ctDNA) Predict Treatment Efficacy and Prognosis in Patients With Advanced Pancreatic Cancer: A Prospective Large‐Cohort Study

MedComm, Volume 7, Issue 7, July 2026.
A total of 127 advanced pancreatic ductal adenocarcinoma (PDAC) patients receiving first‐line therapy were enrolled in this study. A series of peripheral blood collected before the initiation of treatment (B1), at the first response assessment (B2), and at subsequent timepoints to perform high‐depth next‐generation sequencing.
Tingting You, Hui Tang, Mingming Yuan, Dongfeng Song, Chenyu Wang, Jinrong Ying, Rongrong Chen, Chunmei Bai, Yuejuan Cheng, Yingyi Wang   +9 more
wiley   +1 more source

Impact of <i>UGT1A1*28</i> polymorphism in patients with metastatic pancreatic ductal adenocarcinoma treated with NALIRIFOX in the NAPOLI 3 trial. [PDF]

Future Oncol
Abdelrahim M, Khan G, Hatoum H, Zervoudakis A, Dayyani F, Zhang L, Li J, Maxwell F, O'Reilly EM, Wainberg ZA, Bullock A.   +10 more
europepmc   +1 more source

Endobronchial Metastasis From Osteosarcoma in an Adolescent: A Rare Case Report

Thoracic Cancer, Volume 17, Issue 14, July 2026.
Endobronchial metastasis from osteosarcoma is rare. This case of a 14‐year‐old female with tibial osteosarcoma demonstrates an atypical metastatic pathway to the bronchus. She developed respiratory symptoms 13 months after initial treatment, and subsequent bronchoscopic biopsies confirmed endobronchial metastasis.
Yanling He, Yanping Chen, Yanhong Liu, Juyan Chen, Ahmad Muhammad, Huiwen Jin, Yi Xiao   +6 more
wiley   +1 more source

Long-term survival in metastatic abdominal Ewing sarcoma with gastric serosal involvement following first-line irinotecan plus cisplatin: a case report. [PDF]

Front Oncol
Ji L, Li Y, Chen X, Liu Y, Tao W, Wang G, Cui T, Chen Y, Sun H, Jiang N, Wang K.   +10 more
europepmc   +1 more source

Endoscopic Full‐Thickness Resection for Gastrointestinal Subepithelial and Epithelial Neoplasia: Current Status, Indications, and Technical and Oncological Challenges—A Multispecialty Perspective

Digestive Endoscopy, Volume 38, Issue 7, July 2026.
In this review article, we summarized the current status of EFTR for SETs and discussed future clinical applications for epithelial neoplasms from oncological and technical perspectives. EFTR is clinically feasible for treating gastric SETs. Future investigations and technical innovations are required to expand the clinical indications for EFTR in ...
Seiichiro Abe, Kenichiro Imai, Teppei Akimoto, Takashi Kanesaka, Yosuke Minoda, Noriko Nishiyama, Chiko Sato, Akira Ouchi, Hon Chi Yip, Takao Itoi, Mitsuhiro Fujishiro, Yutaka Saito   +11 more
wiley   +1 more source

Enzymatic Laccase Nanoreactors Induce Apoptosis in MOLT-4-ALL Cells and Activate Prodrugs in a Synergetic Effect. [PDF]

Blood Lymphat Cancer
Medrano-Villagómez CA, Loredo-García E, Gasperin-Bulbarela J, Vazquez-Duhalt R.   +3 more
europepmc   +1 more source

Active Helicobacter pylori Infection and Survival Outcomes in De Novo Metastatic Colorectal Cancer: A Retrospective Cohort Study

Helicobacter, Volume 31, Issue 4, July/August 2026.
ABSTRACT Background The prognostic significance of Helicobacter pylori (H. pylori) infection in metastatic colorectal cancer (mCRC) remains uncertain. Most prior studies have focused on colorectal neoplasia risk and have relied on serological markers rather than assessment of active infection.
Sait Kitapli, Ali Alkan, Ozgur Tanriverdi   +2 more
wiley   +1 more source