Results 151 to 160 of about 57,115 (246)
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
Therapeutic Effects of Ceranib-2 and Irinotecan Combination on Colon Cancer. [PDF]
Selvi O +3 more
europepmc +1 more source
Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley +1 more source
Deciphering the Formulation-Dependent Neurotoxicity of Irinotecan: An Integrated Pharmacovigilance and Mechanistic Study. [PDF]
Shen C, Ma W, Lu J, Tang Y, Cao W.
europepmc +1 more source
Reactivation of hepatitis B after irinotecan
Objective: To analyse the incidence of hepatitis B reactivation following treatment with irinotecan-based combined chemotherapy and the outcomes of patients with hepatitis B reactivation.
Kwok, CCH +6 more
core
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley +1 more source
Risk factors for irinotecan-induced hepatotoxicity: a retrospective cohort study. [PDF]
Alherz FA +8 more
europepmc +1 more source
Dual‐drug‐loaded liposomes enable the simultaneous delivery of hydrophilic and hydrophobic therapeutics to tumors, enhancing anticancer efficacy and overcoming multidrug resistance. Through rational formulation design and surface functionalization, these systems improve tumor targeting, modulate efflux mechanisms and EMT, and achieve synergistic ...
Neelam Sinha +4 more
wiley +1 more source
Engineered human adipose-derived stem cells delivering carboxylesterase and TRAIL for castration-resistant prostate cancer: Translational synthesis. [PDF]
Kim JH, Lee SH, Song YS.
europepmc +1 more source
This study assessed neoadjuvant PD‐1 blockade plus chemotherapy in patients with resectable limited‐stage small cell lung cancer. Peri‐treatment biopsy and surgical samples were analyzed using bulk RNA sequencing and bioinformatics approaches.
Shiyue Wan +14 more
wiley +1 more source

