Results 61 to 70 of about 3,601 (174)

Distal Bile Duct Metastasis From Rectal Cancer: The Diagnostic Contribution of Intraductal Ultrasonography

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 49‐year‐old male developed liver dysfunction during chemotherapy for rectal cancer located in the rectosigmoid region. Although magnetic resonance cholangiopancreatography initially indicated sclerosing cholangitis, endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed multiple non‐contiguous intraductal ...
Shinji Monoe, Ryo Nishio, Arihiro Nakano, Yu Yasue, Takahiro Yamashita, Hitoshi Iwata   +5 more
wiley   +1 more source

Self‐Immolative Systems in Diagnostic and Therapeutic Applications

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Self‐Immolative Systems enable the precise, residue‐free release of active molecules, drugs, probes, or sensors, via cyclization or elimination, triggered by specific stimuli. Their versatility drives advances in drug delivery, diagnostics, nanotechnology, materials chemistry, and biosensing, offering chemists control over molecular activation and ...
Windbedema Prisca Ouédraogo, Thomas Cailly, Valérie Collot   +2 more
wiley   +1 more source

Recent Advances in Integrating Graphene into Polymeric Nanocomposite Hydrogels for Biomedical Applications

Macromolecular Bioscience, Volume 26, Issue 2, February 2026.
This review explores recent progress in graphene‐based polymeric nanocomposite hydrogels and how they enhance mechanical strength, electrical conductivity, and biocompatibility. It outlines key fabrication strategies and highlights applications in drug delivery, tissue engineering, and photothermal therapy, while also discussing the emerging role of ...
Abrar Hussain, Irum Batool, Khurram Shahzad, Syed Kumail Hussain Naqvi, Shahzaib Akhter, Ujala Zafar, Khaled Chawraba, Sang Hyun Park   +7 more
wiley   +1 more source

Comparison of DC Bead-irinotecan and DC Bead-topotecan drug eluting beads for use in locoregional drug delivery to treat pancreatic cancer [PDF]

, 2010
DC Bead is a drug delivery embolisation system that can be loaded with doxorubicin or irinotecan for the treatment of a variety of liver cancers. In this study we demonstrate that the topoisomerase I inhibitor topotecan hydrochloride can be successfully ...
Forster, R.E.J., Lloyd, Andrew; id_orcid, Richard E. J. Forster, Yiqing Tang, Phillips, Gary J., Gary J. Phillips, Antonijevic, Milan D., Small, S.A., Antonijevic, M.D., Tang, Yiqing, Wendy Macfarlane, Milan D. Antonijevic, Sharon A. Small, Clare L. Heaysman, Macfarlane, Wendy, Lewis, Andrew L., Lewis, A.L., Forster, Richard E.J., Phillips, Gary, Lloyd, Andrew W., Heaysman, C.L., Macfarlane, Wendy; id_orcid, Andrew L. Lewis, Heaysman, Clare L., Tang, Y., Small, Sharon A., Andrew W. Lloyd   +26 more
core   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application

MedComm, Volume 7, Issue 2, February 2026.
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen, Shan Wu, Yueyang Zhang, Lilu Feng, Yang Chen, Xuzhao Yang, Ke Men, Jiuqun Zhu, Ming Li   +8 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Adjuvant chemotherapy with irinotecan hydrochloride and cisplatin for clear cell carcinoma of the ovary

Oncology Reports, 2006
Clear cell carcinoma (CCC) of the ovary has distinct characteristics showing resistance to conventional platinum-based regimen. Our aim was to evaluate the effects of combination therapy with irinotecan hydrochloride and cisplatin (CPT-P), comparing to regimen with paclitaxel and platinum (TP).
Masashi, Takano, Yoshihiro, Kikuchi, Nobuo, Yaegashi, Mitsuaki, Suzuki, Hiroshi, Tsuda, Satoru, Sagae, Yasuhiro, Udagawa, Kazuo, Kuzuya, Junzo, Kigawa, Satoshi, Takeuchi, Hitoshi, Tsuda, Takuya, Moriya, Toru, Sugiyama   +12 more
openaire   +3 more sources

Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri, Lise Morizur, Simon Dumas, Giacomo Gropplero, Cécile Martinat, Stéphanie Descroix, Claire Wilhelm   +6 more
wiley   +1 more source

Irinotecan hydrochloride (CPT-11) in dialysis patients with gastrointestinal cancer.

Acta medica Okayama, 2010
We investigated changes in drug disposition and toxicities with CPT-11 in 15 dialysis patients with gastrointestinal cancers to clarify whether CPT-11 could be administered safely in such patients. For comparison, the same parameters were also investigated in 10 cancer patients not undergoing dialysis.
Ashizawa, Tatsuto, Iwahori, Tohru, Yokoyama, Takayoshi, Kihara, Yuu, Konnno, Osamu, Jyojima, Yoshimaro, Akashi, Isao, Nakamura, Yuuki, Hama, Kouichirou, Iwamoto, Hitoshi, Segawa, Mai, Takeuchi, Hironori, Hirano, Toshihiko, Nagao, Takeshi   +13 more
openaire   +3 more sources