Results 41 to 50 of about 19,638 (210)

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Long-term experience of surgical removal of iridociliary tumors followed by iridolenticular diaphragm implantation [PDF]

Клиническая офтальмология
A.A. Yarovoy, N.P. Sobolev, A.V. Shatskikh, A.D. Matyaeva S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russian Federation Background: surgical removal of iridociliary tumors is a top-priority method of organ-preserving ...
A.A. Yarovoy, N.P. Sobolev, A.V. Shatskikh, A.D. Matyaeva   +3 more
doaj  

Mature Tertiary Lymphoid Structures Indicate Good Chemotherapy Response and Prognosis in Advanced Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
In advanced colorectal cancer, tumors with mature tertiary lymphoid structures (TLS) exhibited abundant infiltration of CD3‐ and CD8‐positive lymphocytes in both primary and metastatic sites, indicating an activated immune response. The presence of mature TLS was also associated with favorable chemotherapy sensitivity and improved prognosis.
Nobuhiro Hosoi, Chika Komine, Gendensuren Dorjkhorloo, Takuya Shiraishi, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Takehiko Yokobori, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Mycotoxin exposure and human cancer risk : a systematic review of epidemiological studies

, 2020
In recent years, there has been an increasing interest in investigating the carcinogenicity of mycotoxins in humans. This systematic review aims to provide an overview of data linking exposure to different mycotoxins with human cancer risk. Publications (
Castegnaro M., De Ruyck K., Eaton D. L., European Food Safety Authority (EFSA), Forner A., Halabi K., Huang C., Huang X., IARC, IARC, Knutsen H. K., Knutsen H. K., Peraica M., Ramljak D., Steinkellner H., Stephany R. W., The Commission of the European Communities   +16 more
core   +2 more sources

Anifrolumab Treatment Leads to Rapid Reduction in Urinary Biomarkers of Intrarenal Inflammation in Lupus Nephritis: Results From the Phase 2 Randomized Trial

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE) and is partially driven by type I interferon signaling. Anifrolumab, an approved treatment for patients with SLE, has been investigated in a phase 2 trial in patients with LN receiving standard therapy (TULIP‐LN, ClinicalTrials.gov identifier ...
Andrea Fava, Michelle Petri, Patrick G. Gavin, Eszter Csomor, Philip Z. Brohawn, Daniel Muthas, Adam Platt, Catharina Lindholm, Nicola Ferrari   +8 more
wiley   +1 more source

Sommering ring as a source of problems in long-term outcomes of cataract surgery (literature review) [PDF]

Клиническая офтальмология
E.A. Ragozina, E.V. Egorova, O.V. Ermakova, A.O. Direev Novosibirsk Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, Novosibirsk, Russian Federation Secondary cataracts always occur in a late postoperative period of lens ...
E.A. Ragozina, E.V. Egorova, O.V. Ermakova, A.O. Direev   +3 more
doaj  

Orbital granulocytic sarcoma: case report [PDF]

, 2005
Orbital granulocytic sarcoma is a localized tumor consisting of malignant cells of myeloid origin. This tumor may present in association with acute myelogenous leukemia.
Fonseca Junior, Nilson Lopes Da, Manso, Paulo Góis, Nakanami, Deise Mitsuko, Paves, Luis, Seixas, Maria Teresa   +4 more
core   +3 more sources

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

The prognosis of noncutaneous, nonlymphomatous malignancy after heart transplantation: data from the spanish post-heart transplant tumour registry [PDF]

, 2010
[Abstract] Introduction. Malignancy is a major complication in the management of solid organ transplant patients. Skin cancers show a better prognosis than other neoplasms, but not all others are equal: Ideally, patient management must take into account ...
Almenar-Bonet, Luis, Alonso-Pulpón, Luis, Arizón-del-Prado, José M., Blasco-Peiró, Teresa, Brossa, V., Brossa-Loidi, Vicens, Crespo-Leiro, María Generosa, De la Fuente-Galán, Luis, Delgado-Jiménez, Juan F., Díaz Molina, Beatriz, González-Vílchez, Francisco, Manito-Lorite, Nicolás, Muñiz, Javier, Pascual Figal, Domingo A., Romero-Rodríguez, N., Rábago, Gregorio, Villa-Arranz, Adolfo   +16 more
core   +2 more sources