Results 11 to 20 of about 112,766 (248)
Down the Iron Path: Mitochondrial Iron Homeostasis and Beyond
Cells, 2021 Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support ...
Jonathan V. Dietz +2 more
doaj +1 more source
Microbiology Spectrum, 2023 Iron-sulfur [Fe-S] clusters are one of the most ancient and functionally versatile natural biosynthetic prosthetic groups required by various proteins involved in important metabolic processes, including the oxidative phosphorylation of proteins ...
Xingju Song +5 more
doaj +1 more source
Escherichia coli RIC is able to donate iron to iron-sulfur clusters. [PDF]
PLoS ONE, 2014 Escherichia coli RIC (Repair of Iron Centers) is a diiron protein previously reported to be involved in the repair of iron-sulfur proteins damaged by oxidative or nitrosative stresses, and proposed to act as an iron donor.
Lígia S Nobre +6 more
doaj +1 more source
Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis. [PDF]
PLoS ONE, 2009 BACKGROUND:Iron-sulfur clusters are ubiquitous structures which act as prosthetic groups for numerous proteins involved in several fundamental biological processes including respiration and photosynthesis.
Xiang Ming Xu +3 more
doaj +1 more source
Iron-induced changes in the proteome of Trichomonas vaginalis hydrogenosomes. [PDF]
PLoS ONE, 2013 Iron plays a crucial role in metabolism as a key component of catalytic and redox cofactors, such as heme or iron-sulfur clusters in enzymes and electron-transporting or regulatory proteins.
Neritza Campo Beltrán +7 more
doaj +1 more source
Communications Biology, 2023 Iron-sulfur clusters are essential for life and defects in their biosynthesis lead to human diseases. The mechanism of cluster assembly and delivery to cytosolic and nuclear client proteins via the cytosolic iron-sulfur cluster assembly (CIA) pathway is ...
Sheena Vasquez +7 more
doaj +1 more source
The Biochemist, 2012 Iron makes up 35% of the Earth's mass, and is plentiful in its crust (approximately 5%), so it is not surprising that Biology has found many different applications for it. Iron–sulfur (Fe–S) clusters are essential, ubiquitous inorganic cofactors in electron-transport proteins of respiration and photosynthesis, and are responsible for the activity of ...
openaire +1 more source
Structural Basis of RICs Iron Donation for Iron-Sulfur Cluster Biogenesis
Frontiers in Microbiology, 2021 Escherichia coli YtfE is a di-iron protein of the widespread Repair of Iron Centers proteins (RIC) family that has the capacity to donate iron, which is a crucial component of the biogenesis of the ubiquitous family of iron-sulfur proteins.
Liliana S. O. Silva +4 more
doaj +1 more source
Iron–sulfur clusters: from metals through mitochondria biogenesis to disease [PDF]
, 2018 Iron–sulfur clusters are ubiquitous inorganic co-factors that contribute to a wide range of cell pathways including the maintenance of DNA integrity, regulation of gene expression and protein translation, energy production, and antiviral response ...
Cardenas-Rodriguez, Mauricio +2 more
core +1 more source
Modulation of MagR magnetic properties via iron–sulfur cluster binding
Scientific Reports, 2021 Iron–sulfur clusters are essential cofactors found in all kingdoms of life and play essential roles in fundamental processes, including but not limited to respiration, photosynthesis, and nitrogen fixation.
Zhen Guo +11 more
doaj +1 more source