Results 91 to 100 of about 2,116,690 (282)

Molecular MRI Reveals Macrophage‐Enriched Peritumoral Immune Remodeling After Incomplete Ablation in Liver Cancer

Advanced Science, EarlyView.
Incomplete microwave ablation (iMWA) induced a spatially organized, macrophage‐rich immunosuppressive tumor microenvironment (TME) in orthotopic VX2 liver tumors. Molecular MRI enhanced with europium‐doped very small superparamagnetic iron oxide nanoparticles (Eu‐VSOP) noninvasively visualized this remodeling, showing preferential nanoparticle ...
Yubei He, Han Xu, Julian M. M. Rogasch, Nikolaus Berndt, Jing Guo, Eyk Schellenberger, Akvile Häckel, Luisa Heidemann, Friederike Hesse, Yu Liu, Justus Ramtke, Nicola Beindorff, Frank Hofheinz, Avan Kader, Michael Mülleder, Kathrin Textoris‐Taube, Bernd Hamm, Dominik N. Müller, Robin Schmidt, Ralf Hauptmann, Heike Traub, Mathias Schannor, Lynn Jeanette Savic   +22 more
wiley   +1 more source

An IscS Persulfide Donates the Sulfur for Ribosomal Protein uL16 Thioamidation

Angewandte Chemie, EarlyView.
YcaO‐catalyzed thioamidation of the ribosomal subunit protein uL16 is widespread in Pseudomonadota bacteria. We identify the iron–sulfur cluster cysteine desulfurase IscS as the sulfur donor via an IscS persulfide and observe direct IscS–uL16 interactions.
Yanqing Xue, Markus W. Voehler, Douglas A. Mitchell   +2 more
wiley   +2 more sources

Pulsed electric field (PEF)-processed 6-shogaol-rich ginger extract protects β-Thalassemic red blood cells from iron-induced oxidative stress and hemolysis.

PLoS ONE
β- thalassemia is the genetic blood disorder characterized by ineffective beta-globin chain synthesis. The increased iron absorption and frequently blood transfusion result in iron overload and the production of reactive oxygen species (ROS).
Hataichanok Chuljerm, Narisara Paradee, Kornvipa Settakorn, Somdet Srichairatanakool, Artit Yawootti, Kanokwan Kulprachakarn, Wason Parklak, Pimpisid Koonyosying   +7 more
doaj   +1 more source

Iron chelators as mitophagy agents: Potential and limitations

Biomedicine & Pharmacotherapy
Mitochondrial autophagy (mitophagy) is very important process for the maintenance of cellular homeostasis, functionality and survival. Its dysregulation is associated with high risk and progression numerous serious diseases (e.g., oncological, neurodegenerative and cardiovascular ones). Therefore, targeting mitophagy mechanisms is very hot topic in the
Brogyanyi Tereza, Kejik Zdenek, Vesela Katerina, Dytrych Petr, Hoskovec David, Masařík Michal, Babula Petr, Kaplanek Robert, Pribyl Tomas, Zelenka Jaroslav, Ruml Tomas, Vokurka Martin, Martasek Pavel, Jakubek Milan   +13 more
openaire   +3 more sources

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

Advanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao, Wenbo He, Zhenlin Ouyang, Ruochen Wang, Jiaxin Zhang, Xin Liu, Yiting Jing, Qinyue Yu, Xiaoyu He, Qian Qin, Litao Guo, Peter M. Hwang, Fang Zheng, Yurong Wen   +13 more
wiley   +1 more source

S = 3/2 Iron(I)‐Bisphosphine‐Ate Complexes: Synthesis, Characterization, and Reactivity for Electrophile Activation

Angewandte Chemie, EarlyView.
In this work, we present a new class of unusual charged Fe(I)‐bisphosphine‐ates, along with full characterization of their structure and bonding, utilizing low‐temperature synthetic and spectroscopic and techniques. These complexes are highly reactive toward catalytically relevant electrophiles, and can serve as valuable synthons providing access to ...
Egor Kokin, Shih‐Chieh Kao, Matthew J. Kania, Michael L. Neidig   +3 more
wiley   +2 more sources

Use of a Chelating Agent for Accelerating Excretion of Radio-Iron

Experimental Biology and Medicine, 1952
Summary1. Excretion of parenterally administered radio-iron is approximately 5 to 10 times as great in feces as in urine. The rate of excretion varies with the location of the tracer within the various iron pools in the body, (for example, cells, liver, reticulo-endo-thelial system, etc.).
H, FOREMAN, R L, HUFF, J M, ODA, J, GARCIA   +3 more
openaire   +2 more sources

Iron(III) chelating resins X. Iron detoxification of human plasma with iron(III) chelating resins [PDF]

, 1993
Iron detoxification of human blood plasma was studied with resins containing desferrioxamine B (DFO) or 3-hydroxy-2-methyl-4(1H)-pyridinone (HMP) as iron(III)-chelating groups.
Feng, M.H., Bantjes, A., van der Does, L.   +2 more
core   +1 more source

Surface‐State‐Driven Selectivity of Electrocatalytic Glucose Oxidation: Metallic Au, Au─OH, and CuO

Advanced Science, EarlyView.
In the electrochemical oxidation of glucose, whether the pyranose ring opens upon adsorption decides the reaction pathway: ring opening on metallic Au yields gluconic acid, gluconolactone formation on Au─OH leads to glucaric acid, and C─C cleavage on CuO gives formic acid. Surface state thus governs product selectivity.
Myeonghwan Oh, Hoeun Seong, Ga Eun Jo, Jiyoung Hwang, Yurim Sohn, Kyoungsuk Jin, Jong Hyeok Park, Wooyul Kim, Seok Ki Kim, Dong Ki Lee   +9 more
wiley   +1 more source

From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries

Advanced Energy Materials, EarlyView.
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku, Sangbin Park, Sunha Hwang, Sunghyun Lim, Won‐Sub Yoon, Jongsoon Kim   +5 more
wiley   +1 more source