Results 201 to 210 of about 2,116,690 (282)

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

Artesunate in Ferroptosis and Cuproptosis Regulation: Context-Dependent Mechanisms, Interplay, and Therapeutic Implications. [PDF]

Int J Mol Sci
Feng K, Xia Y, Liu J, Yang M.
europepmc   +1 more source

Butin Ameliorates Atherosclerosis by Regulating the TIMM13‐TIMM8A Complex to Alleviate Macrophage Ferroptosis

Phytotherapy Research, EarlyView.
The natural flavonoid Butin selectively targets the mitochondrial translocase subunit TIMM13 at residue Asn34, competitively disrupting the pathological TIMM13‐TIMM8A complex. This targeted engagement halts mitochondrial iron influx, reactivates the SLC7A11/GPX4 antioxidant cascade, and attenuates macrophage ferroptosis and foam cell formation ...
Dashuai Wang, Xinyi Yu, Mingjie Xie, Gongcheng Huang, Zhenxing Liang, Chen Huang, Hai Liu   +6 more
wiley   +1 more source

Stage-dependent activity of curcumin-rosmarinic acid against Leishmania donovani: Synergy in amastigotes. [PDF]

PLoS Negl Trop Dis
Moore CAA, Donkor JK, Yamthe LRT, Tiengwe C, Gwira TM.   +4 more
europepmc   +1 more source

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

Phytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng, Xuelian Yuan, Yawen Xie, Zhenni Xia, Zhaohui Guo, Xuesong Liu, Rong Li, Wenliang Wang   +7 more
wiley   +1 more source

Ferric pyrophosphate in precision iron fortification: mechanistic insights into food-system suitability, bioavailability modulation, and evaluation strategies. [PDF]

Food Chem X
Wang Y, Wei Y, Chang M, No J, Liu K.
europepmc   +1 more source

Emerging Approaches for Phytoconstituent Delivery in the Management of Rheumatoid Arthritis: Bridging Nature and Nanotechnology

Phytotherapy Research, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is an autoimmune condition marked by joint inflammation, cartilage destruction, and bone damage. Conventional treatments, including NSAIDs and DMARDs, have shown effectiveness in slowing down disease progression, but prolonged exposure to such medications results in adverse effects and lack of tolerance among patients.
Yogesh Khairnar, Sakshi Priya, Madhavi Rajpara, Venkatesh K. P. Rao, Geeta Bhatt, Gautam Singhvi   +5 more
wiley   +1 more source

Green Tea Extract Attenuates Oxidative Stress and Prolongs Red Blood Cell Survival in Iron-Overloaded β-Thalassemic Mice. [PDF]

Antioxidants (Basel)
Zhong Y, Ounjaijean S, Srichairatanakool S, Paradee N, Yubo S, Xu H, Koonyosying P, Phannasil P, Svasti S, Srichairatanakool S.   +9 more
europepmc   +1 more source

Machine learning‐driven advances in carbon‐based quantum dots: Opportunities accompanied by challenges

Responsive Materials, EarlyView.
Machine learning provides a unifying framework to connect structure, fluorescence properties, and applications of carbon‐based quantum dots. This review highlights how data‐driven strategies enable fluorescence regulation, reveal underlying mechanisms, and accelerate the rational design of functional carbon dots.
Liangfeng Chen, Siwei Yang, Xiangqian Cui, Ziheng Liu, Hang Wang, Yongqiang Li, Peng He, Miao Wang, Guqiao Ding   +8 more
wiley   +1 more source

TPEN-Advanced Metal Chelator: From Characterization to Biomedical Applications. [PDF]

Molecules
Rydel-Ciszek K.
europepmc   +1 more source