Results 41 to 50 of about 2,116,690 (282)

In vivo evaluation of microglia activation by intracranial iron overload in central pain after spinal cord injury

Journal of Orthopaedic Surgery and Research, 2017
Background Central pain (CP) is a common clinical problem in patients with spinal cord injury (SCI). Recent studies found the pathogenesis of CP was related to the remodeling of the brain.
Fan Xing Meng, Jing Ming Hou, Tian Sheng Sun   +2 more
doaj   +1 more source

New advance for disease modification therapy in Parkinson's disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Therapy to halt or slow down the progression of neurodegeneration in Parkinson's disease (PD) is urgently demand. Disease modification therapy can modify the natural history of the disease and show neuroprotective effect in PD.
OU Ru⁃wei, SHANG Hui⁃fang
doaj   +1 more source

Chelating agent free solid phase extraction (CAF-SPE) method for separation and/or preconcentration of iron(III) ions

, 2010
This paper presents a chelating agent free solid phase extraction (CAF-SPE) method for the separation and/or preconcentration of trace iron(III) ions. This method is based on the sorption of Fe(III) ions without using any chelating agent onto Amberlyst ...
Turker, Ali Rehber, YALÇINKAYA, ÖZCAN, Kalfa, Orhan Murat   +2 more
core   +1 more source

Protective Effects of Deferoxamine on Vestibulotoxicity in Gentamicin-Induced Bilateral Vestibulopathy Rat Model

Frontiers in Neurology, 2021
Introduction: Administration of aminoglycoside (AG) antibiotics is one of the most common causes of ototoxicity. This study aimed to determine the protective effects of deferoxamine, an iron-chelating agent, on vestibulotoxicity using an intratympanic ...
Hyo-Jung Kim, Jin-Ok Lee, Ji-Soo Kim, Ji-Soo Kim   +3 more
doaj   +1 more source

The Interaction of Chelating Agents with Bacteria

, 1958
The interaction of solutions containing oxine or iron or both (in a 1:1 molar ratio) with Staph, aureus is examined with respect to the chelating agent and metal ion binding by the bacteria.
A H Beckett, Ann E Robinson, A A Vahora
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Ameliorating Effects of Aqueous Extract of Tetracarpidium conophorhum against Iron- Overload Induced damage in Rats

Journal of Applied Sciences and Environmental Management, 2020
Iron, though an important nutrient but in excess can produce serious damaging effects on organs of the body. Intake of plants and or plant products with iron chelating ability, instead of synthetic iron chelators, can produce less adverse effects and ...
S.O. Innih, N. Eluehike, O. Ikponmwosa-Eweka   +2 more
doaj   +1 more source

Remote Activation of Wnt Signaling and Cell Proliferation by E‐Cadherin Magnetomechanical Stimulation

Advanced Functional Materials, EarlyView.
A pioneering magnetogenetic toolkit enables non‐invasive, precise spatiotemporal modulation of intracellular Wnt/β‐catenin signaling. Functionalized magnetic nanoparticles (MNPs@E/EC15) target cellular E‐cadherins to generate localized magnetomechanical forces under low‐intensity magnetic fields.
Christian Castro‐Hinojosa, Pablo Martínez‐Vicente, Lucía G. Recaredo, Susel Del Sol‐Fernández, Pilar Gomollón‐Zueco, Yilian Fernández‐Afonso, Raluca M. Fratila, María Moros   +7 more
wiley   +1 more source

Markers of Renal Complications in Beta Thalassemia Patients with Iron Overload Receiving Chelation Agent Therapy: A Systematic Review

Journal of Blood Medicine, 2022
Pradana Zaky Romadhon,1,2 Ami Ashariati,3 Siprianus Ugroseno Yudho Bintoro,3 Mochammad Thaha,2 Satriyo Dwi Suryantoro,2 Choirina Windradi,2 Bagus Aulia Mahdi,3 Dwiki Novendrianto,3 Krisnina Nurul Widiyastuti,3 Okla Sekar Martani,3 Etha Dini Widiasi,3 ...
Romadhon PZ, Ashariati A, Bintoro SUY, Thaha M, Suryantoro SD, Windradi C, Mahdi BA, Novendrianto D, Widiyastuti KN, Martani OS, Widiasi ED, Agustin ED, Prabowo E, Putra YR, Thahadian HF, Adhikara IM, Adyarini DD, Prahasanti K, Putri AE, Yusoff NM   +19 more
doaj  

Iron chelators: as therapeutic agents in diseases

Annals of Medicine & Surgery
The concentration of iron is tightly regulated, making it an essential element. Various cellular processes in the body rely on iron, such as oxygen sensing, oxygen transport, electron transfer, and DNA synthesis. Iron excess can be toxic because it participates in redox reactions that catalyze the production of reactive oxygen species and elevate ...
Salimi, Zohreh, Afsharinasab, Mehdi, Rostami, Mehdi, Eshaghi Milasi, Yaser, Mousavi Ezmareh, Seyedeh Fatemeh, Sakhaei, Fariba, Mohammad-Sadeghipour, Maryam, Rasooli Manesh, Sayyed Mehdi, Asemi, Zatollah   +8 more
openaire   +2 more sources