Results 111 to 120 of about 53,650 (299)

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine. [PDF]

Sci Rep, 2022
Hašková P, Applová L, Jansová H, Homola P, Franz KJ, Vávrová K, Roh J, Šimůnek T.   +7 more
europepmc   +1 more source

Evaluation of diffusive gradients in thin-films using a Diphonix® resin for monitoring dissolved uranium in natural waters [PDF]

, 2015
Commercially available Diphonix® resin (TrisKem International) was evaluated as a receiving phase for use with the diffusive gradients in thin-films (DGT) passive sampler for measuring uranium.
Amos, Sean, Burnett, Jonathan L., Fones, Gary R., Mills, Graham A., Turner, Geraldine S. C.   +4 more
core   +2 more sources

Iron chelators as therapeutic agents against Pneumocystis carinii [PDF]

Antimicrobial Agents and Chemotherapy, 1994
Iron plays a critical role in host-parasite interactions, and iron chelators have been demonstrated to serve as effective adjunct therapeutic agents against malaria. The effects of the parenteral iron chelator deferoxamine (DFO) on the growth of rat-derived Pneumocystis carinii were studied in a human fibroblast cell culture model and in two in vivo ...
openaire   +2 more sources

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Bacillus anthracis Siderophores

Проблемы особо опасных инфекций, 2016
Iron is an essential for growth and reproduction of bacteria element. One of the ways of its acquisition by Bacillus anthracis is utilization of high-affinity chelating agents of iron ions - bacillibactin and petrobactin siderophores, extracting the iron
E. I. Eremenko
doaj   +1 more source

Long-Term Effects of Iron Chelating Agents on Ocular Function in Patients with Thalassemia Major. [PDF]

Clin Ophthalmol, 2021
Nuzzi R, Geronazzo G, Tridico F, Nuzzi A, Caselgrandi P, Piga AG.   +5 more
europepmc   +1 more source

Selective inhibition of carotenoid cleavage dioxygenases : phenotypic effects on shoot branching [PDF]

, 2009
Members of the carotenoid cleavage dioxygenase family catalyse the oxidative cleavage of carotenoids at various chain positions, leading to the formation of a wide range of apocarotenoid signalling molecules.
Auldridge, Zeevaart, Schwartz, von Lintig, Wyss, Kiefer, Hu, Dudareva, Bouvier, Juttner, Kloer, Marasco, Eisner, Fester, Matusova, Akiyama, Gomez-Roldan, Umehara, Ward, Sorefan, Booker, Schwartz, Alder, Booker, Bennett, Cunningham, Schwartz, Stockwell, Armstrong, Kaschani, Han, Kitahata, Suzuki, Han, Bergeron, Kawase, Schmidt, Cunningham, Wilson, Chatfield, Taylor, Borowski, Kontogiorgis, Simkin, Burbidge, Vogel, Paik, Scherzinger, Bouvier, Quinlan, Walter, Yeh, Alija   +52 more
core   +1 more source

SYNTHETIC CHELATING AGENTS IN IRON METABOLISM* [PDF]

Journal of Clinical Investigation, 1963
F, CLETON, A, TURNBULL, C A, FINCH
openaire   +2 more sources

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source