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Metal-Chelating Macroalgal Extract as a Marine Antioxidant for Stabilizing DHA Nanoemulsions. [PDF]
Antioxidants (Basel)Ghelichi S +6 more
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Iron chelating agents for the treatment of iron overload
Coordination Chemistry Reviews, 2008The importance of iron chelators in medicine has significantly increased in recent years. Iron is essential for life but it is also potentially more toxic than other trace elements. This is because we lack effective means to protect human cells against iron overload and because of the role of iron in the generation of free radicals. In order to protect
Guido Crisponi, Maurizio Remelli
exaly +2 more sources
Iron chelating agents in clinical practice
Coordination Chemistry Reviews, 1999Abstract The relevance of iron chelators in medicine has increased in recent years. Iron is essential for life but it is also potentially more toxic than other trace elements. This is due to the lack of effective means to protect human cells against iron overload and to the role of iron in the generation of free radicals. To protect patients from the
Guido Crisponi, Gavino Faà
exaly +3 more sources
Silybin, a new iron-chelating agent
Journal of Inorganic Biochemistry, 2001Silybin, a natural occurring flavolignan isolated from the fruits of Silibum marianum, has been reported to exert antioxidant and free radical scavenging abilities. It was suggested to act also as an iron chelator. The complexation and protonation equilibria of the ferric complex of this compound have been studied by potentiometric, spectrophotometric ...
BORSARI, Marco +6 more
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Iron-Chelating Agents in Non-Iron Overload Conditions
Annals of Internal Medicine, 1994To review the current clinical experience with iron chelators in non-iron overload conditions.The English-language literature was searched from 1983 through 1992 manually and using MEDLINE.Original articles, case reports, and abstracts addressing iron chelation.Selected reports that described clinical applications of iron chelators in non-iron overload
E E, Voest, G, Vreugdenhil, J J, Marx
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Iron chelators as therapeutic iron depletion agents
Expert Opinion on Therapeutic Patents, 2006The great promise of iron depletion as a therapeutic strategy for various diseases, including iron overload, cancers, Alzheimer’s disease, Parkinson’s disease, tuberculosis, HIV, and fungal and malaria infection, has stimulated research on the development of iron chelators as iron depletion agents.
Noah Birch, Xiang Wang, Hyun-Soon Chong
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The Effect of Chelating Agents on Cellular Iron Metabolism
Clinical Science, 19761. The effect of iron chelators on iron uptake, ferritin and total protein synthesis was studied in cultured Chang cells. Desferrioxamine depressed ferritin synthesis and completely inhibited iron uptake by ferritin protein. Rhodotorulic acid reduced iron uptake by the cells but had little effect on ferritin synthesis.
G P, White, R, Bailey-Wood, A, Jacobs
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Mobilization of ferritin iron in erythroblasts by chelating agents
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1985Intracellular ferritin in newt (Triturus cristatus) erythroblasts was accessible to the chelating effects of EDTA and pyridoxal phosphate. EDTA (0.5-1 mM) promoted release of radioactive iron from ferritin of pulse-labelled erythroblasts during chase incubation, but its continuous presence was not necessary for ferritin iron mobilization.
J A, Grasso +2 more
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EFFECT OF AN IRON‐CHELATING AGENT ON LYMPHOCYTE PROLIFERATION
Australian Journal of Experimental Biology and Medical Science, 1984SummaryThe effect of the iron‐chelating: agent desferrioxamine on lymphocyte proliferation has been studied. Desferrioxamine at concentrations of 15 μM totally inhibited the proliferation of Concanavalin A‐stimulated lymphocytes, whereas iron‐saturated desferrioxamine was ineffective.
N, Bowern +3 more
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