Results 271 to 280 of about 21,036 (302)

Hetrombopag, an Emerging Iron-Chelating Agent, Alleviates Systemic Iron Overload

Blood
Background: Iron overload is a syndrome in which excessive iron accumulates in the body, leading to tissue damage and functional disorders. This condition is common in patients with refractory anaemia who receive long-term red blood cell transfusions.
Zhao Yufei, Xin Zhao, Wenrui Yang, Fengkui Zhang   +3 more
openaire   +1 more source

Iron-chelating therapy with the new oral agent ICL670 (Exjade®)

Best Practice & Research Clinical Haematology, 2005
Iron-chelation therapy is essential in iron-overloaded patients. The long-term efficacy of this approach has been demonstrated unequivocally with deferoxamine, which effectively controls iron concentrations, thereby limiting organ damage and preventing premature death.
openaire   +2 more sources

New Chelating Agents for Trivalent Iron

Science, 1953
S, CHABEREK, F C, BERSWORTH
openaire   +2 more sources

Therapeutic iron-chelating agents

1994
S. SINGH, R.C. HIDER
openaire   +1 more source

SYNTHETIC AMINO ACID CHELATING AGENTS AND IRON METABOLISM*

Annals of the New York Academy of Sciences, 1960
M, RUBIN, J V, PRINCIOTTO
openaire   +2 more sources

Therapeutic Use of Chelating Agents in Iron Overload

1995
Elemental iron, like molecular oxygen, is a highly toxic substance that is nevertheless essential for life. Therefore, like oxygen, complex biochemical systems have evolved for its safe delivery, transport, and utilization. Iron absorption in the human gut is a highly regulated process that depends in part on total body iron stores (FLanagan 1990 ...
openaire   +1 more source

Oral iron chelating agents

Reactions, 1988
openaire   +1 more source

Potential Iron(III)-chelating agents for treatment of Iron overload

2002
...
FERRARI, Erika, GRANDI, Romano, SALADINI, Monica   +2 more
openaire   +1 more source

Mobilization of iron from ferritin by chelating agents

Biochemistry, 1968
L, Pape, J S, Multani, C, Stitt, P, Saltman   +3 more
openaire   +2 more sources

Targeting iron metabolism in drug discovery and delivery

Nature Reviews Drug Discovery, 2017
Bart J Crielaard, Twan Lammers, Stefano Rivella   +2 more
exaly