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Hetrombopag, an Emerging Iron-Chelating Agent, Alleviates Systemic Iron Overload
BloodBackground: Iron overload is a syndrome in which excessive iron accumulates in the body, leading to tissue damage and functional disorders. This condition is common in patients with refractory anaemia who receive long-term red blood cell transfusions.
Zhao Yufei +3 more
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Iron-chelating therapy with the new oral agent ICL670 (Exjade®)
Best Practice & Research Clinical Haematology, 2005Iron-chelation therapy is essential in iron-overloaded patients. The long-term efficacy of this approach has been demonstrated unequivocally with deferoxamine, which effectively controls iron concentrations, thereby limiting organ damage and preventing premature death.
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New Chelating Agents for Trivalent Iron
Science, 1953S, CHABEREK, F C, BERSWORTH
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Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Steven P Rowe, Martin G Pomper
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SYNTHETIC AMINO ACID CHELATING AGENTS AND IRON METABOLISM*
Annals of the New York Academy of Sciences, 1960M, RUBIN, J V, PRINCIOTTO
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Therapeutic Use of Chelating Agents in Iron Overload
1995Elemental iron, like molecular oxygen, is a highly toxic substance that is nevertheless essential for life. Therefore, like oxygen, complex biochemical systems have evolved for its safe delivery, transport, and utilization. Iron absorption in the human gut is a highly regulated process that depends in part on total body iron stores (FLanagan 1990 ...
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Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
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