Results 31 to 40 of about 277,097 (267)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A Combined Experimental and Finite Element Analysis Method for the Estimation of Eddy-Current Loss in NdFeB Magnets

Sensors, 2014
NdFeB permanent magnets (PMs) are widely used in high performance electrical machines, but their relatively high conductivity subjects them to eddy current losses that can lead to magnetization loss.
Radu Fratila, Abdelkader Benabou, Abdelmounaïm Tounzi, Jean-Claude Mipo   +3 more
doaj   +1 more source

Empirical Implementation of the Steinmetz Equation to Compute Eddy Current Loss in Soft Magnetic Composite Components

IEEE Access, 2022
Finite element analysis of magnetic materials allows accurate prediction of losses and is crucial in the design of electromagnetic devices and products.
Mehmet C. Kulan, Nick J. Baker, Konstantinos A. Liogas, Oliver Davis, John Taylor, Alexander M. Korsunsky   +5 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Measurement of Iron Loss Using Rotational Magnetic Loss Measurement Apparatus

IEEE Translation Journal on Magnetics in Japan, 1990
Several methods have been proposed for the measurement of the magnetic losses in electrical steel sheet under the condition of rotating flux. The method considered here is based on a determination of the fied quantities and makes use of square-shaped samples and an air gap between the pole faces and the sample.
M. Enokizono, T. Suzuki, J. D. Sievert
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Calculation and Study of Permanent Magnet Synchronous Motor Iron Loss

Kongzhi Yu Xinxi Jishu, 2015
Taking into account of rotational magnetization and harmonic magnetic field, a calculation method of iron loss for permanent magnet synchronous motor (PMSM) was presented , which was based on finite element analysis and Bertotti iron loss calculation ...
PENG Jun, LI Yifeng, FU Minli
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Efficiency Analysis and Optimization of Two-Speed-Region Operation of Permanent Magnet Synchronous Motor Taking into Account Iron Loss Based on Linear Non-Equilibrium Thermodynamics

Machines
In this article, the linear non-equilibrium thermodynamic approach is used to mathematically describe the energy regularities of an interior permanent magnet synchronous motor (IPMSM), taking into account iron loss. The IPMSM is considered a linear power
Ihor Shchur, Yurii Biletskyi, Bohdan Kopchak   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source