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Current Opinion in Hematology, 2004
Hepcidin is a recently discovered hepatic peptide that regulates intestinal iron absorption as well as maternal-fetal iron transport across the placenta. It probably also affects the release of iron from hepatic stores and from macrophages involved in the recycling of iron from hemoglobin.
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Hepcidin is a recently discovered hepatic peptide that regulates intestinal iron absorption as well as maternal-fetal iron transport across the placenta. It probably also affects the release of iron from hepatic stores and from macrophages involved in the recycling of iron from hemoglobin.
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Perspectives in Iron Metabolism
New England Journal of Medicine, 1982IN early times the earth had a reducing atmosphere, and an abundance of ferrous iron was present for incorporation into biologic molecules.1 Later, with an increase in atmospheric oxygen, iron existed largely in its less available ferric form,2 and special devices had to be developed by life forms for the acquisition of iron.
C A, Finch, H, Huebers
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The American Journal of Clinical Nutrition, 1990
Humans can adapt successfully to a wide range of iron requirements and intakes. The lower limit of the adapted state is best defined by serum ferritin greater than or equal to 12 micrograms/L, because lower values indicate that iron stores are fully depleted.
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Humans can adapt successfully to a wide range of iron requirements and intakes. The lower limit of the adapted state is best defined by serum ferritin greater than or equal to 12 micrograms/L, because lower values indicate that iron stores are fully depleted.
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The American Journal of Clinical Nutrition, 1977
An important component of nonspecific defense of vertebrates against microbial invasion is that of nutritional immunity. Hosts attempt to withhold growth-essential iron from invading bacteria, fungi, and protozoa. Clinical conditions in which hosts are stressed by excess quantities of iron in specific fluids, tissues, or cells result in enhanced ...
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An important component of nonspecific defense of vertebrates against microbial invasion is that of nutritional immunity. Hosts attempt to withhold growth-essential iron from invading bacteria, fungi, and protozoa. Clinical conditions in which hosts are stressed by excess quantities of iron in specific fluids, tissues, or cells result in enhanced ...
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Clinical Laboratory
The essential trace element iron, which can occur in various oxidation states, is required for many biochemical reactions and processes in the human body.This review summarizes the current knowledge about the physiology of iron metabolism.The physiological functions comprise oxygen transport in the blood, electron transport processes, DNA synthesis and
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The essential trace element iron, which can occur in various oxidation states, is required for many biochemical reactions and processes in the human body.This review summarizes the current knowledge about the physiology of iron metabolism.The physiological functions comprise oxygen transport in the blood, electron transport processes, DNA synthesis and
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