Iron metabolism in trypanosomatids, and its crucial role in infection. [PDF]
, 2010 Iron is almost ubiquitous in living organisms due to the utility of its redox chemistry. It is also dangerous as it can catalyse the formation of reactive free radicals - a classical double-edged sword.
Kelly, JM, Taylor, MC
core +1 more source
Hepcidin and sports anemia [PDF]
, 2014 Iron is an important mineral element used by the body in a variety of metabolic and physiologic processes. These processes are highly active when the body is undergoing physical exercises. Prevalence of exercise-induced iron deficiency anemia (also known
Guofen Gao, Wei-Na Kong, Yan-Zhong Chang
core +2 more sources
Inflammation, dysregulated iron metabolism, and cardiovascular disease
Frontiers in Aging, 2023 Iron is an essential trace element associated with both pathologic deficiency and toxic overload. Thus, systemic and cell iron metabolism are highly controlled processes regulated by protein expression and localization, as well as turnover, through the ...
Shaina L. Rosenblum
doaj +1 more source
Pyoverdine and proteases affect the response of pseudomonas aeruginosa to gallium in human serum [PDF]
, 2015 Gallium is an iron mimetic which has recently been repurposed as an antibacterial agent due to its capability to disrupt bacterial iron metabolism. In this study, the antibacterial activity of gallium nitrate [Ga(NO3)3] was investigated in complement ...
Bonchi, Carlo +3 more
core +1 more source
CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism
Antioxidants, 2023 CHIR99021 is an aminopyrimidine derivative, which can efficiently inhibit the activity of glycogen synthesis kinase 3α (GSK-3α) and GSK-3β. As an essential component of stem cell culture medium, it plays an important role in maintaining cell stemness ...
Yingying Han +8 more
doaj +1 more source
Iron Metabolism: From Health to Disease [PDF]
, 2014 Background Iron is vital for almost all living organisms by participating in a wide range of metabolic processes. However, iron concentration in body tissues must be tightly regulated since excessive iron may lead to microbial infections or cause tissue
Fernandes, Rúben +2 more
core +1 more source
Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
, 2014 Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
core +1 more source
Iron Metabolism in Normal and Pathological Pregnancies and Fetal Consequences
Metabolites, 2022 Iron is required for energy production, DNA synthesis, and cell proliferation, mainly as a component of the prosthetic group in hemoproteins and as part of iron-sulfur clusters.
Charles Mégier +3 more
doaj +1 more source
Snapshot of iron response in by gene network reconstruction [PDF]
, 2009 Background Iron homeostasis of Shewanella oneidensis, a γ-proteobacterium possessing high iron content, is regulated by a global transcription factor Fur.
Yunfeng Yang +11 more
core +1 more source
Low Dose Daily Iron Supplementation Improves Iron Status and Appetite but not Anemia, Whereas Quarterly Anthelminthic Treatment Improves Growth, Appetite and Anemia in Zanzibari Preschool Children. [PDF]
, 2004 Iron deficiency and helminth infections are two common conditions of children in developing countries. The consequences of helminth infection in young children are not well described, and the efficacy of low dose iron supplementation is not well ...
Adam +53 more
core +1 more source