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Physiology of Iron Metabolism [PDF]
Transfusion Medicine and Hemotherapy, 2014 A revolution occurred during the last decade in the comprehension of the physiology as well as in the physiopathology of iron metabolism. The purpose of this review is to summarize the recent knowledge that has accumulated, allowing a better comprehension of the mechanisms implicated in iron homeostasis. Iron metabolism is very fine tuned.
Waldvogel-Abramowski S +6 more
openaire +4 more sources
Einstein (São Paulo), 2005 The present paper deals with iron metabolism, from its absorption,regulatory factors, storage, and distribution to body compartmentsaccording to existing knowledge.
Ana Maria de Souza
doaj +1 more source
Modulation of Iron Metabolism in Response to Infection: Twists for All Tastes
Pharmaceuticals, 2018 Iron is an essential nutrient for almost all living organisms, but is not easily made available. Hosts and pathogens engage in a fight for the metal during an infection, leading to major alterations in the host’s iron metabolism.
Ana Cordeiro Gomes +3 more
doaj +3 more sources
Identification of an iron–hepcidin complex [PDF]
, 2008 Following its identification as a liver-expressed antimicrobial peptide, the hepcidin peptide was later shown to be a key player in iron homoeostasis. It is now proposed to be the 'iron hormone' which, by interacting with the iron transporter ferroportin,
Bui, T.T.T. +23 more
core +5 more sources
Elucidating Iron Metabolism through Molecular Imaging
Current Issues in Molecular BiologyIron is essential for many physiological processes, and the dysregulation of its metabolism is implicated in the pathogenesis of various diseases.
Feifei Liao +9 more
doaj +2 more sources
Rhabdomyolysis after Intravenous Ferric Gluconate: A Case Report
European Journal of Case Reports in Internal Medicine, 2022 Patients with severe iron deficiency, malabsorption or intolerance to oral iron are frequently treated with intravenous iron replacement. We report the case of a 42-year-old woman with non-erosive oligoarticular arthritis with antiparietal cell ...
Mara Botti +3 more
doaj +1 more source
The emerging role of furin in neurodegenerative and neuropsychiatric diseases
Translational Neurodegeneration, 2022 Furin is an important mammalian proprotein convertase that catalyzes the proteolytic maturation of a variety of prohormones and proproteins in the secretory pathway.
Yi Zhang +5 more
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Iron metabolism and iron disorders revisited in the hepcidin era
Haematologica, 2020 Iron is biologically essential, but also potentially toxic; as such it is tightly controlled at cell and systemic levels to prevent both deficiency and overload.
Clara Camaschella +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2022 PKAN disease is caused by mutations in the PANK2 gene, encoding the mitochondrial enzyme pantothenate kinase 2, catalyzing the first and key reaction in Coenzyme A (CoA) biosynthetic process.
Maddalena Ripamonti +8 more
doaj +1 more source
Redox Biology, 2022 Oxidative stress and deficient bioenergetics are key players in the pathological process of cerebral ischemia reperfusion injury (I/R). As a mitochondrial iron storage protein, mitochondrial ferritin (FtMt) plays a pivotal role in protecting neuronal ...
Peina Wang +6 more
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