Results 11 to 20 of about 484,048 (304)

Ferroportin Is Essential for Iron Absorption During Suckling, But Is Hyporesponsive to the Regulatory Hormone HepcidinSummary

Cellular and Molecular Gastroenterology and Hepatology, 2017
Background & Aims: Previous studies have suggested that iron absorption in suckling mammals is refractory to stimuli that normally would decrease absorption in adults.
David M. Frazer, Sarah J. Wilkins, Deepak Darshan, Cornel S.G. Mirciov, Linda A. Dunn, Gregory J. Anderson   +5 more
doaj   +1 more source

Iron economy in Chlamydomonas reinhardtii. [PDF]

, 2013
While research on iron nutrition in plants has largely focused on iron-uptake pathways, photosynthetic microbes such as the unicellular green alga Chlamydomonas reinhardtii provide excellent experimental systems for understanding iron metabolism at the ...
Blaby-Haas, Crysten E, Glaesener, Anne G, Merchant, Sabeeha S   +2 more
core   +1 more source

Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells

Cell Death and Disease, 2022
Brain iron dysregulation associated with aging is closely related to motor and cognitive impairments in neurodegenerative diseases. The regulation of iron traffic at the blood-brain barrier (BBB) is crucial to maintain brain iron homeostasis.
Linhao You, Pan-Pan Yu, Tianyu Dong, Wenhuan Guo, Shiyang Chang, Bingjie Zheng, Yunzhe Ci, Fudi Wang, Peng Yu, Guofen Gao, Yan-Zhong Chang   +10 more
doaj   +1 more source

Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories. [PDF]

, 2016
Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Adibhatla, Aghajanian, Alazami, Alderson, Andrews, Balboa, Balsinde, Barbeito, Beck, Bosveld, Bras, Bras, Breus, Brissot, Broekemeier, Brunetti, Burn, Campanella, Chen, Cozzi, Crichton, Cui, Curtis, Dall'Armi, Daugherty, Davis, Deas, Dehay, Deng, Deschauer, Di Fonzo, Dick, Duran, Dusi, Eckhardt, Edvardson, Elbaz-Alon, Engel, Friedman, Fukunaga, Gadd, Gitler, Gonzalez-Cuyar, Green, Gregory, Gregory, Grünewald, Haack, Hailey, Hallgren, Hama, Hamasaki, Hartig, Hartig, Hayflick, Hayflick, Hill, Hogarth, Hong, Hortnagel, Houlden, Hönscher, Itoh, Iuso, Jana, Jenkins, Jeong, Jiang, Jin, Kaneko, Keller, Keogh, Kondo, Kono, Kotzbauer, Kruer, Kruer, Kruer, Kruer, Kurz, Kühlbrandt, Landouré, Larsson, Lei, Leonardi, Leoni, Levi, Li, Liou, Lu, Maday, Mahadevan, Malik, Mancuso, Manjithaya, Mariño, McNeill, Moreno, Morgan, Morita, Nemazanyy, Nousbeck, Oide, Ong, Paisan-Ruiz, Paisán-Ruiz, Park, Perry, Pivtoraiko, Poli, Polishchuk, Potter, Proikas-Cezanne, Ramirez, Ramonet, Rana, Riku, Ross, Ross, Rouault, Rouault, Roy, Saitsu, Scherz-Shouval, Schmidt, Schneider, Schneider, Seleznev, Shinzawa, Siudeja, Song, Strokin, Strokin, Tan, Tooze, Tsunemi, Usenovic, Vidal, Walia, Williams, Wu, Xu, Yadrick, Yang, Yoshida, Yoshida, Zhang, Zhou, Zorzi   +148 more
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Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis

Cell Death and Disease, 2021
Ischaemic stroke is becoming the most common cerebral disease in aging populations, but the underlying molecular mechanism of the disease has not yet been fully elucidated.
Peina Wang, Yanmei Cui, Qianqian Ren, Bingqi Yan, Yashuo Zhao, Peng Yu, Guofen Gao, Honglian Shi, Shiyang Chang, Yan-Zhong Chang   +9 more
doaj   +1 more source

Overexpression of Mitochondrial Ferritin Enhances Blood–Brain Barrier Integrity Following Ischemic Stroke in Mice by Maintaining Iron Homeostasis in Endothelial Cells

Antioxidants, 2022
Blood–brain barrier (BBB) breakdown, a characteristic feature of ischemic stroke, contributes to poor patient outcomes. Brain microvascular endothelial cells (BMVECs) are a key component of the BBB and dysfunction or death of these cells following ...
Peina Wang, Qianqian Ren, Mengtong Shi, Yuanyuan Liu, Huiyuan Bai, Yan-Zhong Chang   +5 more
doaj   +1 more source

Nitrate-Dependent Iron Oxidation: A Potential Mars Metabolism [PDF]

, 2018
This work considers the hypothetical viability of microbial nitrate-dependent Fe2+ oxidation (NDFO) for supporting simple life in the context of the early Mars environment.
Abramov, Amils, Anand, Arevalo, Arnold, Arvidson, Bauermeister, Benz, Bibring, Bridges, Bridges, Bruce, Busigny, Byrne-Bailey, Cabrol, Canfield, Carlson, Carlson, Carr, Chakraborty, Chakraborty, Changela, Charlou, Chassefière, Chastain, Chaudhuri, Chevrier, Cockell, Cockell, Cockell, Comeau, Czaja, Dartnell, Edwards, Edwards, Edwards, Ehlmann, Ehlmann, Ehlmann, Ehrenreich, Emerson, Emerson, Emerson, Etique, Ettwig, Fassett, Filiberto, Fisk, Formisano, Fowler, Fox, Fox, Fox-Powell, Frydenvang, Gauger, Gendrin, Glavin, Grady, Gronstal, Grotzinger, Grotzinger, Hafenbradl, Hecht, Hedrich, Hicks, Hoefen, Hoehler, Hoppert, Hurowitz, Ilbert, Ionescu, Irwin, Jakosky, Jepsen, Johnson, Kappler, Kappler, Kappler, King, Kish, Klueglein, Klueglein, Konhauser, Konn, Kounaves, Kumaraswamy, Lack, Lalonde, Lanza, Laufer, Lopez-Reyes, Lovley, Lovley, Madigan, Mahaffy, Malin, Mangold, Manning, Martin, Martín-Torres, Marzo, McSween, McSween, Michalski, Millero, Ming, Ming, Miot, Miot, Miot, Miot, Miot, Miot, Miot, Miot, Mirvaux, Montoya, Morgan, Morris, Morris, Morris, Muehe, Myers, Nachon, Navarro-González, Nealson, Nie, Nixon, Nixon, Nixon, Oren, Osinski, Palucis, Pantke, Parnell, Pirajno, Popa, Raghoebarsing, Raiswell, Ramirez, Rampe, Rampe, Reimers, Revsbech, Roden, Santelli, Schieber, Schuerger, Schwenzer, Schwenzer, Schädler, Sephton, Sholes, Smith, Smith, Squyres, Squyres, Squyres, Steele, Stern, Stern, Stevens, Straub, Straub, Straub, Strohm, Summers, Summers, Summers, Sutter, Toporski, Tosca, Tosca, Tuff, Vaniman, Visscher, Wacey, Weber, Weber, Weber, Webster, Welhan, Wheat, Williams, Yen, Yen   +185 more
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Subchronic dietary exposure of rats to cadmium alters the metabolism of metals essential to bone health [PDF]

, 2004
Cadmium (Cd) was recently identified as a risk factor for osteoporosis. Skeletal damage may be the critical effect of low-level long-term exposure to Cd in the general population exposed via food, but the mechanisms behind this are not clearly understood.
Guérin, Thierry, Kolf-Clauw, Martine, Noël, Laurent   +2 more
core   +1 more source

Cellular iron metabolism [PDF]

Kidney International, 1999
Iron is essential for oxidation-reduction catalysis and bioenergetics, but unless appropriately shielded, iron plays a key role in the formation of toxic oxygen radicals that can attack all biological molecules. Hence, specialized molecules for the acquisition, transport (transferrin), and storage (ferritin) of iron in a soluble nontoxic form have ...
openaire   +2 more sources

Altered sterol metabolism in budding yeast affects mitochondrial iron–sulfur (Fe-S) cluster synthesis [PDF]

, 2018
Ergosterol synthesis is essential for cellular growth and viability of the budding yeast Saccharomyces cerevisiae, and intracellular sterol distribution and homeostasis are therefore highly regulated in this species. Erg25 is an iron-containing C4-methyl
Bard, Martin, Bhuiyan, Shah Alam, Chen, Opal S., Cox, James E., Kaplan, Jerry, Li, Liangtao, Natarajan, Selvamuthu K., Ward, Diane M.   +7 more
core   +1 more source