AbstractIron overload/toxicity is an unavoidable consequence in several diseases characterized by anemia and red blood cell transfusion requirement. Iron toxicity can impact on transplant outcome by increasing oxidative stress. Impact of iron toxicity is different in the different stages of HCT.
Emanuele Angelucci, Anna Maria Raiola
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International Journal of Hematology-Oncology and Stem Cell Research, 2015 Currently, hematopoietic stem cell transplantation (HSCT) is the only curative option for patients with beta-thalassemia major, but liver iron overload in these patients will not decrease and hepatic fibrosis may still progress despite successful HSCT ...
Ardeshir Ghavamzadeh +4 more
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