Results 171 to 180 of about 129,076 (346)
AbstractIron overload/toxicity is an unavoidable consequence in several diseases characterized by anemia and red blood cell transfusion requirement. Iron toxicity can impact on transplant outcome by increasing oxidative stress. Impact of iron toxicity is different in the different stages of HCT.
Emanuele Angelucci, Anna Maria Raiola
openaire +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera +12 more
wiley +1 more source
Increased calcification by erythrophagocytosis in aortic valvular interstitial cells
ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin +3 more
wiley +1 more source
Iron body stores in patients treated with red-cell transfusions
Zdravniški Vestnik, 2007 Background: Consequence of chronic transfusion therapy is a secondary iron overload, which adversely affects the heart, liver and endocrine glands. This can be minimized by iron chelating therapy.
Uroš Mlakar
doaj
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen +7 more
wiley +1 more source
International Journal of Hematology-Oncology and Stem Cell Research, 2015 Currently, hematopoietic stem cell transplantation (HSCT) is the only curative option for patients with beta-thalassemia major, but liver iron overload in these patients will not decrease and hepatic fibrosis may still progress despite successful HSCT ...
Ardeshir Ghavamzadeh +4 more
doaj
Spleen iron, molybdenum, and manganese concentrations are coregulated in hepcidin‐deficient and secondary iron overload models in mice [PDF]
, 2019 Thibault Cavey +10 more
openalex +1 more source
Scour‐Conditioned Seismic Fragility Analysis of Monopile‐Supported Offshore Wind Turbines
Earthquake Engineering &Structural Dynamics, EarlyView.ABSTRACT Monopile‐supported offshore wind turbines (MS‐OWTs) are increasingly deployed in seismic coastal regions, where they face compound risks from earthquake loading and seabed scour. While past studies have addressed these hazards separately, seismic fragility under evolving scour conditions remains insufficiently understood. This study introduces
Francisco Pinto +3 more
wiley +1 more source
Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration
Exploration, EarlyView.This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao +11 more
wiley +1 more source