Results 181 to 190 of about 1,016,828 (293)

Nicotinamide Mononucleotide Combined Glucose Counteracts Iron Overload-Induced Mitochondrial Dysfunction in Mice Under Hypobaric Hypoxia. [PDF]

Mol Cell Proteomics
Tan F, Huang X, Mao X, Wang Y, Wang X, Tang F, Chen X, Mao R, Gong X, Chen L, Di LJ, Zhang S, Zeng J, Lin SH.   +13 more
europepmc   +1 more source

Amyloid‐β–Related Cortical Susceptibility Alterations in Individuals Under Assessment for Alzheimer's Disease: A χ‐Separation Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Assessment of amyloid‐β (Aβ) burden and associated iron deposition and neurodegeneration is important for Alzheimer's disease (AD) management. Although quantitative susceptibility mapping (QSM) detects iron and myelin changes, conventional metrics suffer from signal cancelation between paramagnetic and diamagnetic components ...
Hiroyuki Tatekawa, Tatsushi Oura, Akitoshi Takeda, Ayako Omori, Natsuko Atsukawa, Shu Matsushita, Daisuke Horiuchi, Hirotaka Takita, Yasuhito Mitsuyama, Yoshihito Ban, Taro Shimono, Josef Pfeuffer, Daiju Ueda, Yoshiaki Itoh, Yukio Miki   +14 more
wiley   +1 more source

Steroid Biosynthesis Pathway Counteracts Iron Overload-Induced Ferroptosis in Mouse Granulosa Cells. [PDF]

Biology (Basel)
Gao F, Mao W, He X, Liu Y, Liu Y, Liu S, Liu J, Ma L.   +7 more
europepmc   +1 more source

An LRRK2 variant blocks NCOA4 trafficking upon iron overload, leading to ferroptotic death. [PDF]

J Cell Sci
Goldman A, Nguyen M, Lanoix J, Li C, Fahmy A, Xu YZ, Schurr E, Thibault P, Desjardins M, McBride HM.   +9 more
europepmc   +1 more source

MRI Proton Density Fat Fraction as a Biomarker of Marrow Recovery Following Organ‐Sparing Total Marrow Irradiation in Sickle Cell Disease

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Noninvasive quantitative assessment of marrow recovery after curative therapies such as total marrow irradiation (TMI) and bone marrow transplantation (BMT) remain poorly defined, particularly in sickle cell disease (SCD). Purpose To evaluate MRI‐derived proton density fat fraction (PDFF) as a biomarker of marrow recovery following ...
Malakeh Malekzadeh, Hemendra Ghimire, Ji Eun Lim, Srideshikan S. Madabushi, Weidong Hu, Marco Andrea Zampini, Kazuki Fujita, Raghda Fouda, Guy Storme, Joo Song, Bihong T. Chen, Anna Pawlowska, Susanta K. Hui   +12 more
wiley   +1 more source

Iron overload suppresses LKB1 and induces IL36G anti-tumor immunity in PDAC metastasis. [PDF]

Sci Adv
Biancur DE, Venkatesh H, Crawford A, Jeong Y, Sohn ASW, Kapner KS, Yamamoto K, Lin EY, Banh RS, Assi M, Shapiro B, Yu P, Song SC, Coetzee WA, Aguirre AJ, Jones AN, Kimmelman AC, Possemato R.   +17 more
europepmc   +1 more source

Measurements of Liver and Bone Marrow Proton Density Fat Fraction in the Setting of Ferumoxytol‐Enhanced MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Proton density fat fraction (PDFF) is typically measured using confounder‐corrected, multi‐echo, gradient‐recalled‐echo chemical‐shift‐encoded (CSE)‐MRI. Ferumoxytol, an iron‐based MRI contrast agent, increases liver and bone marrow (BM) R2*, a major confounder of PDFF.
Lukas Müller, Srijyotsna Volety, Jan‐Peter Grunz, Fatemeh Rashidi, Scott B. Reeder, Diego Hernando, Ali Pirasteh   +6 more
wiley   +1 more source

Tropolone and hinokitiol act against <i>Staphylococcus aureus</i> by concentration-dependent iron restriction or toxic iron overload. [PDF]

mSphere
Hardman BL, Sharples GJ.
europepmc   +1 more source

Multicenter, Multivendor Development and Validation of Automated Liver Prescription

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Manual prescription of liver MRI volumes introduces inter‐operator variability and prolongs exam duration. Artificial intelligence (AI)‐based prescription has been demonstrated, but existing work has been limited to single‐vendor settings. Purpose To develop and validate an AI model for automated liver MRI prescription using a large,
Garrett C. Fullerton, Jitka Starekova, Collin J. Buelo, David T. Harris, Raphael do Vale Souza, Aaron Faacks, Alexandra A. Anagnostopoulos, Veronica P. Christofi, Austin Murphy, Diana Kadi, Takeshi Yokoo, Mustafa R. Bashir, Scott B. Reeder, Diego Hernando   +13 more
wiley   +1 more source

Dose-Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload. [PDF]

Adv Sci (Weinh)
Li F, Wu Y, Yang G, Lai J, Sun X, Wang L, Li X, Zhang J, Zhang Q, Chen H, Lin H, Xu B, Zhang J, Wang H, Meng A, Cao C, Cao C.   +16 more
europepmc   +1 more source