Senotherapeutics for Knee Osteoarthritis
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
Iron Chelation Therapy in Iron Overload Disorders: A Systematic Review with Narrative Synthesis of Bioenergetic Dysfunction, Oxidative Stress, and Biomarker-Guided Management. [PDF]
Alburayh KAS, Emara AM, Elgharabawy RM.
europepmc +1 more source
Commentary on Ferumoxytol and Beyond: Navigating the Shift Away From GBCAs in Neuro‐Oncology
Journal of Magnetic Resonance Imaging, EarlyView.
Vera C. Keil, Yelda Özsunar
wiley +1 more source
ABSTRACT Purpose This study aimed to assess the feasibility of QSM in the human kidney during free‐breathing using respiratory gating for motion compensation. Methods Renal imaging of 15 healthy volunteers was performed using an axial multi‐echo GRE sequence on a 3 T MRI scanner.
Matthias Deitermann +7 more
wiley +1 more source
Hereditary Hyperferritinemia Cataract Syndrome Mimicking Iron Overload in a Pediatric Patient With Coexisting HFE H63D Homozygosity. [PDF]
Yiğit Y, Çelebi HBG.
europepmc +1 more source
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith +5 more
wiley +1 more source
Pancreatic Iron Overload Is Associated With Early QTc Prolongation Before Myocardial Iron Deposition in Transfusion-Dependent Thalassemia. [PDF]
Meloni A +12 more
europepmc +1 more source
Abstract Background Studies show increased use of home enteral nutrition (HEN) owing to its benefits. However, knowledge about the sanitary risks of handling home‐prepared formulas remains limited despite their high contamination rates. This study aimed to assess the sanitary risks in the handling of home‐prepared enteral formulations by analyzing ...
Marcelly Caroline Pires Fernandes +6 more
wiley +1 more source
A Ferric Ammonium Citrate-Based Model of Iron Overload With Ferroptosis-Associated Readouts In C2C12 Myoblasts. [PDF]
Wacker EE +3 more
europepmc +1 more source
Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell +6 more
wiley +1 more source

