Results 161 to 170 of about 1,016,828 (293)

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Cardiovascular Aging and Damage in Patients with Iron Overload. [PDF]

Biomedicines
Gruszecki M, Młodziński K, Świątczak M, Gruszecka A, Bujnowski A, Lewandowska A, Karmoliński S, Kaufmann D, Daniłowicz-Szymanowicz L.   +8 more
europepmc   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Iron Overload: Pathophysiology, Diagnosis and Monitoring. [PDF]

Int J Lab Hematol
Chatzikalil E, Delaporta P, Bistas K, Kattamis A.   +3 more
europepmc   +1 more source

A Comprehensive Review of Fault‐Current Limiter Technologies for Smart and Resilient Power Systems

Energy Science &Engineering, EarlyView.
This review compares superconducting, solid‐state, and hybrid fault‐current limiters (FCLs) for modern alternating current, direct current, and hybrid grids. It shows that optimal FCL selection depends on fault characteristics, network configuration, voltage level, protection coordination, and resilience requirements rather than on a universally ...
Abdelrahman Farghly, Eslam Essam, Hilmy Awad, Samia Abdelfatah, Walid Issa, Abdallah M. Hamada   +5 more
wiley   +1 more source

Combination Therapy With Proton Pump Inhibitors and Iron Chelators in Hereditary Anaemias With Secondary Iron Overload. [PDF]

EJHaem
Doeven T, van Vuren A, Glenthøj A, Kerkhoffs JL, Schols SEM, Rijneveld A, Nur E, Peereboom D, Welsing P, Schutgens R, Biemond BJ, van Beers EJ.   +11 more
europepmc   +1 more source

Ferroptosis in necrotizing enterocolitis: iron overload-driven intestinal injury and mechanistic insights. [PDF]

Front Pediatr
Huang Q, Zeng L, Wei B, Wei Q, Li R, Qin L, Chen Q, Chen Y.   +7 more
europepmc   +1 more source

Analysis of various electrocardiographic and echocardiographic parameters in beta thalassemia patients with iron overload. [PDF]

Ann Pediatr Cardiol
Girija H, Sridhar A, Muthukumaran CS, Ramkishore S, Ganesan R, Mahitha V, Arun V.   +6 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source