Results 51 to 60 of about 426,340 (247)

Cross-relaxation and temporal dynamics of lasing at 2 μm in thulium-doped ceramic material

High Power Laser Science and Engineering
We report the characterization of the pump absorption and emission dynamic properties of a $\mathrm{Tm}:{\mathrm{Lu}}_2{\mathrm{O}}_3$ ceramic lasing medium using a three-mirror folded laser cavity.
Alessandro Fregosi, Fernando Brandi, Luca Labate, Federica Baffigi, Gianluca Cellamare, Mohamed Ezzat, Daniele Palla, Guido Toci, Alex Whitehead, Leonida A. Gizzi   +9 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications

Instruments
Laser-accelerated electron beams, in the so-called Very High-Energy Electron (VHEE) energy range, are of great interest for biomedical applications.
David Gregocki, Petra Köster, Luca Umberto Labate, Simona Piccinini, Federico Avella, Federica Baffigi, Gabriele Bandini, Fernando Brandi, Lorenzo Fulgentini, Daniele Palla, Martina Salvadori, Simon Gerasimos Vlachos, Leonida Antonio Gizzi   +12 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Sulfonated Graphene Oxide Doped Imidazolium-Functionalized PVDF Ion Exchange Membrane with Enhanced Ion Conductivity

Membranes
A novel membrane was synthesized in this work by grafting 1-vinyl-3-ethylimidazolium tetrafluoroborate ([C2VIm][BF4]) onto a polyvinylidene fluoride (PVDF) backbone, followed by the introduction of a sulfonated graphene oxide (SGO) dispersion into the ...
Jiangtao Yu, Wenkang Li, Wei Niu, Manman Zhang, Junqing Bai, Pengtao Li, Liang Wang, Yuqing Cui, Shuanfang Cui, Xueyan Que, Jun Ma, Long Zhao   +11 more
doaj   +1 more source

Probing the linear polarization of photons in ultraperipheral heavy ion collisions

Physics Letters B, 2019
We propose to measure the linear polarization of the external electromagnetic fields of a relativistic heavy ion through azimuthal asymmetries in dilepton production in ultraperipheral collisions.
Cong Li, Jian Zhou, Ya-jin Zhou
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Preparation process and performance of graphene oxide-doped UO2 pellets

He jishu
BackgroundUranium dioxide (UO2) has been broadly employed as nuclear fuel in nuclear reactors. However, the poor thermal conductivity of UO2 compromises the safety of the reactor owing to possible sharp temperature gradients.
WEN Feng, DU Jiangping, ZHAO Yumeng, YANG Ning, SHAO Zongyi, LIU Wei, CAI Zhenfang   +6 more
doaj   +1 more source