Results 61 to 70 of about 1,249,952 (349)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Ionizing radiation effects on CMOS imagers manufactured in deep submicron process [PDF]

, 2008
We present here a study on both CMOS sensors and elementary structures (photodiodes and in-pixel MOSFETs) manufactured in a deep submicron process dedicated to imaging.
, , Franck Corbière, Frédéric Bernard, Guy Rolland, Nicolas Huger, Olivier Saint-Pé, Pierre Magnan, Vincent Goiffon   +8 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Machine learning predictions of irradiation embrittlement in reactor pressure vessel steels

npj Computational Materials, 2022
Irradiation increases the yield stress and embrittles light water reactor (LWR) pressure vessel steels. In this study, we demonstrate some of the potential benefits and risks of using machine learning models to predict irradiation hardening extrapolated ...
Yu-chen Liu, Henry Wu, Tam Mayeshiba, Benjamin Afflerbach, Ryan Jacobs, Josh Perry, Jerit George, Josh Cordell, Jinyu Xia, Hao Yuan, Aren Lorenson, Haotian Wu, Matthew Parker, Fenil Doshi, Alexander Politowicz, Linda Xiao, Dane Morgan, Peter Wells, Nathan Almirall, Takuya Yamamoto, G. Robert Odette   +20 more
doaj   +1 more source

Properties of Potassium Doped and Tantalum Containing Tungsten after Heavy Ion Irradiation

Crystals, 2023
Tungsten potassium (WK) alloy has been reported as one of the ideal plasma-facing materials (PFMs). Tantalum alloying is a good method to improve the mechanical properties of tungsten.
Juan Du, Chuan Wu, Tianyu Zhao, Pan Wen, Pinghuai Wang, Jun Tang, Xiang Liu, Jiming Chen   +7 more
doaj   +1 more source

Lattice dynamics for isochorically heated metals: A model study

, 2019
The electron-excitation induced bond strength variations in metals have been predicted from density-functional theory calculations and observed experimentally, while the microscopic mechanism has yet to be elucidated.
Ono, Shota
core   +1 more source

Multiscale modeling of crystal plasticity in Reactor Pressure Vessel steels: Prediction of irradiation hardening

Journal of Nuclear Materials, 2019
The plastic behavior of irradiated Reactor Pressure Vessel (RPV) steels is described by constitutive equations capturing the temperature and strain rate sensitivities.
G. Monnet, L. Vincent, L. Gélébart
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Radiation Effects in Pinned Photodiode CMOS Image Sensors: Pixel Performance Degradation Due to Total Ionizing Dose [PDF]

, 2012
Several Pinned Photodiode (PPD) CMOS Image Sensors (CIS) are designed, manufactured, characterized and exposed biased to ionizing radiation up to 10 kGy(SiO2 ).
Cervantes, Paola, Corbière, Franck, Estribeau, Magali, Gaillardin, Marc, Girard, Sylvain, Goiffon, Vincent, Magnan, Pierre, Marcandella, Claude, Marcelot, Olivier, Martin-Gonthier, Philippe, Molina, Romain, Paillet, Philippe, Virmontois, Cédric   +12 more
core   +3 more sources

Insights into the sources of irradiation hardening in a neutron irradiated 304L stainless steel following post-irradiation annealing

, 2019
The 304L SS was irradiated in Barseback 1 BWR reactor to 5.9 dpa followed by post-irradiation annealing at 500 °C and 550 °C up to 20 h. Correlations of irradiation hardening with the main hardening features of dislocation loops and Ni/Si-rich clusters ...
Z. Jiao, J. Hesterberg, G. Was
semanticscholar   +1 more source