Results 111 to 120 of about 3,861 (149)

Paraneoplastic Isaacs' Syndrome

Journal of Clinical Neuromuscular Disease, 2012
Abstract Objective: Isaacs' syndrome is a rare disease resulting from hyperexcitability of peripheral nerves causing continuous muscle fiber activity characterized by muscle twitching and stiffness at rest and delayed muscle relaxation after voluntary contraction.
Sandeep S, Rana, Ramnath Santosh, Ramanathan, George, Small, Brenda, Adamovich   +3 more
openaire   +2 more sources

Isaacs syndrome: A syndrome of continuous muscle-fiber activity

Neuroscience and Behavioral Physiology, 1981
Within the large group of neuromuscular diseases, in addition to the often-encountered and well-studied diseases there exist rare forms of pathology which are poorly known to the broad circle of practicing physicians. The absence of information concerning these illnesses in textbooks and handbooks leads to difficulties in diagnosis and, consequently ...
N A, Il'ina, , Aver'yanov YuN, V B, Biryukov, M V, Luk'yanov, , Mozolevskii YuV, N F, Polyakova   +5 more
openaire   +2 more sources

Systematic Review of the Clinical Characteristics and Management of Isaac Syndrome

Journal of Clinical Neuromuscular Disease, 2023
Abstract Objectives: Isaac syndrome (IS) is a condition characterized by peripheral nerve hyperexcitability caused by voltage-gated potassium channel (VGKC)-complex antibodies. Muscle twitching, stiffness, hypertrophy, and dysautonomic characteristics, such as hyperhidrosis, are common manifestations. The syndrome can
Mustafa Al-Chalabi, Prajwal Hegde, Sara R. Moore, Yasmeen Abouainain, Myles Keener, Hira Parvez, Jeremy Eid, Sidra Saleem, Ajaz Sheikh   +8 more
openaire   +2 more sources

Isaacs syndrome with laryngeal involvement

Neurology, 1979
A woman with widespread myokymia presented initially at age 19 with hoarseness and mild dyspnea on exertion. The diagnosis of Isaacs syndrome was suggested by the clinical findings of widespread continuous muscle activity and depressed tendon reflexes, although she lacked the usually prominent increased muscle tone.
D L, Jackson, S, Satya-Murti, L, Davis, D B, Drachman   +3 more
openaire   +2 more sources

Isaacs syndrome.

Archives of physical medicine and rehabilitation, 1984
Although Isaacs syndrome is known by several names including neuromyotonia and quantal squander, it bears some resemblence to other syndromes characterized by muscular stiffness such as stiff-man syndrome. The purpose of this paper is to examine pertinent clinical findings about Isaacs syndrome.
openaire   +1 more source

Isaacs' Syndrome With Muscle Hypertrophy Reversed by Phenytoin Therapy

Archives of Neurology, 1983
A 16-year-old boy was seen for severe episodic muscle cramps and generalized myokymia, consistent with Isaacs's syndrome. Bilateral calf hypertrophy (46-cm calf circumference) and ankle areflexia were noted. He was treated with phenytoin sodium, 300 mg/day.
J, Zisfein, M, Sivak, A M, Aron, A N, Bender   +3 more
openaire   +2 more sources

Isaacs syndrome with CASPR2 antibody: A series of three cases

Journal of Clinical Neuroscience, 2017
Isaacs syndrome is a form of peripheral nerve hyperexcitability, characterized by spontaneous muscle twitching and stiffness. Some patients are reported to be positive for CASPR2 antibody that may be one of the pathogenic autoantibodies in Isaacs syndrome.
Jie, Song, Sisi, Jing, Chao, Quan, Jun, Lu, Xiangyang, Qiao, Kai, Qiao, Jiahong, Lu, Jianying, Xi, Chongbo, Zhao   +8 more
openaire   +2 more sources

A Case of Hemi‐Isaac's Syndrome

Movement Disorders Clinical Practice, 2021
Snigdha Komakulu, Pranjal Gupta, Abhishek Anand, Animesh Das, Awadh Kishor Pandit, Achal Kumar Srivastava   +5 more
openaire   +2 more sources

[Syndrome of constant muscle fiber activity (Isaacs syndrome)].

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979
Two cases with expressed signs of a permanent muscular tension in the extremities with fasciculation (the Isaacs syndrome) and difficulties in self-service are described. In both cases the diagnosis was verified by typical EEG changes and a good effect from the use of a diphenylhydantoin or finlepsin.
N A, Il'ina, Iu N, Aver'ianov, V B, Biriukov, M V, Luk'ianov, Iu V, Mozolevskiĭ   +4 more
openaire   +1 more source

[A case of Isaacs' syndrome associated with dextrocardia].

Revista de neurologia, 2002
Isaacs syndrome is a disorder of unknown etiology characterized by muscular rigidity, cramps and myokymias. Described by Isaacs in 1961 and called by him as continuous muscular activity syndrome. There are few reports in Latino american countries.A 31 year-old man with sustained muscular contractions in lower limbs and diffuse myokymias since he was ...
L, Torres, C, Cosentino, M, Vélez, A, Anicama   +3 more
openaire   +1 more source