Results 251 to 260 of about 23,803 (294)

Asymmetric (4 + 3) and (4 + 1) Annulations of Isatin-derived Morita-Baylis-Hillman Carbonates to Construct Diverse Chiral Heterocyclic Frameworks.

Organic Letters, 2020
A chiral tertiary amine-catalyzed asymmetric γ-regioselective (4 + 3) annulation reaction of isatin-derived Morita-Baylis-Hillman carbonates and 1-azadienes was developed, delivering chiral azepane spirooxindoles with excellent stereoselectivity.
Ru‐Jie Yan, Bao‐Xin Liu, Ben-Xian Xiao, Wei Du, Yingchun Chen   +4 more
semanticscholar   +1 more source

Indole/isatin‐containing hybrids as potential antibacterial agents

Archiv der Pharmazie, 2020
The emergence and worldwide spread of drug‐resistant bacteria have already posed a serious threat to human life, creating the urgent need to develop potent and novel antibacterial drug candidates with high efficacy.
Feng Song, Zhenghua Li, Yunqiang Bian, Xiankai Huo, Junman Fang, Linlin Shao, Meng Zhou   +6 more
semanticscholar   +1 more source

ChemInform Abstract: CONDENSATION OF INDOLE WITH ISATIN

Chemischer Informationsdienst, 1976
AbstractDie Indole (I) reagieren in Gegenwart von Diäthylamin mit den Isatinen (II) in Äthanol zu Indolyl‐oxindolen (III), die mit verdünnter Natronlauge bei 95°C zu Oxindolyl‐indolyl‐indolen (IV) und mit Hydrazinhydrat zu den Verbindungen (V) isomerisiert werden.
L. P. Sinyavskaya, G. I. Zhungietu
openaire   +3 more sources

Development of a high-performance anion exchange membrane using poly(isatin biphenylene) with flexible heterocyclic quaternary ammonium cations for alkaline fuel cells

Journal of Materials Chemistry A, 2019
A series of quaternary ammonium-tethered poly(isatin biphenylene)s (PIBs) were prepared devoid of alkaline labile aryl ether bonds via superacid-catalyzed polymerization and explored as highly alkaline stable backbones of anion exchange membranes (AEMs).
Shuai Zhang, X. Zhu, Cuihong Jin
semanticscholar   +1 more source

Isatin‐1,2,3‐triazole‐isatin Scaffolds and Their Antibacterial Activity

Journal of Heterocyclic Chemistry, 2019
Twelve novel isatin‐1,2,3‐triazole‐isatin scaffolds 5a–l were designed, synthesized, and assessed for their in vitro antibacterial activity in this paper. The preliminary results showed that all dimers only endowed with weak antibacterial activity, which was less active than the reference ciprofloxacin.
Ruijing Cheng, Xinjia Yan, Zhi Xu
openaire   +2 more sources

Novel isatin thiosemicarbazone derivatives as potent inhibitors of β-amyloid peptide (Αβ) aggregation and toxicity.

ACS Chemical Neuroscience, 2020
Inhibition of the amyloid β-peptide (Αβ) aggregation of Alzheimer's disease (AD) is among the therapeutic approaches against AD which still attracts scientific research interest.
M. Sagnou, B. Mavroidi, A. Kaminari, N. Boukos, M. Pelecanou   +4 more
semanticscholar   +1 more source

The loss of CO and HCN in the fragmentation of isatin and the methyl isatins

Organic Mass Spectrometry, 1971
Abstract3‐13C‐Isatin has been shown to eliminate the 2‐carbonyl group as the initial fragment, followed predominantly by loss of HCN. In 4‐, 5‐and 6‐methyl‐isatin the loss of the second carbonyl group competes evenly with HCN loss, whilst the 7‐methyl isomer fragments almost exclusively by successive loss of two molecules of CO from the molecular ion.
openaire   +2 more sources

Reaction of (chloromethyl)thiirane with isatins

Russian Journal of Organic Chemistry, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A. A. Tomashevskii, A. N. Butkevich, A. A. Potekhin, V. V. Sokolov   +3 more
openaire   +3 more sources

Organocatalyzed Dearomative Cycloaddition of 2-Nitrobenzofurans and Isatin-Derived Morita-Baylis-Hillman Carbonates: Highly Stereoselective Construction of Cyclopenta[ b]benzofuran Scaffolds.

Organic Letters, 2019
The first organocatalyzed asymmetric dearomative cycloaddition between 2-nitrobenzofurans and isatin-derived Morita-Baylis-Hillman carbonates has been developed.
Jian‐Qiang Zhao, Lei Yang, Xiao-Jian Zhou, Yong You, Zhen-Hua Wang, Ming Zhou, Xiaomei Zhang, Xiao‐Ying Xu, Weicheng Yuan   +8 more
semanticscholar   +1 more source

Isatin hybrids and Their Pharmacological Investigations.

Mini-Reviews in Medical Chemistry, 2020
Hybridization is an important strategy to design molecules that can be effectively used to treat fatal diseases known to mankind. Molecular hybrids and their pharmacological investigations aided to discover several potent isatin (Indole 2, 3 dione ...
B. Varpe, A. Kulkarni, S. Jadhav, Anil S. Mali, S. Jadhav   +4 more
semanticscholar   +1 more source