Results 71 to 80 of about 240,454 (314)
Age-related maculopathy in the light of ischaemia
, 2007 This manuscript focuses on the pathogenesis of age-related maculopathy (ARM) and the documentation of new treatments in ARM. Ischaemia will be given special consideration, as it is believed to play a central role in both early ARM and late ARM or age ...
Feigl, Beatrix
core +1 more source
A metabolomic analysis of cardiac metabolism in a human model of early myocardial ischaemia [PDF]
, 2022 Introduction: Acute myocardial ischaemia and the transition from reversible to irreversible myocardial injury are associated with abnormal metabolic patterns. Advances in metabolomics have extended our capabilities to define these metabolic perturbations
Chacko, Sanoj Mathew
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Paradoxical digital ischaemia [PDF]
BMJ Case Reports, 2010 A young lady presented with an 8-day history of cramping pain in her right hand with ischaemic index and middle fingers (figure 1). Examination revealed no palpable pulses in the right upper limb, no aneurysms, thrills or audible heart murmurs. An electrocardiogram was normal.
N, Shahi, R, Nair
openaire +2 more sources
Endothelin and the ischaemic heart [PDF]
, 2005 Soon after its identification as a powerful vasoconstrictor peptide, endothelin (ET-1) was implicated as a detrimental agent involved in determining the outcome of myocardial ischaemia and reperfusion.
McCabe, C., Kane, K.A., Wainwright, C.L.
core
Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen [PDF]
, 2014 The effects of hypoxia on gene expression have been vigorously studied, but possible effects of small changes in oxygen tension have never been addressed.
Sukhodub, Andriy +9 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Evaluation of Gene Therapy as an Intervention Strategy to Treat Brain Injury from Stroke
Frontiers in Molecular Neuroscience, 2016 Stroke is a leading cause of death and disability, with a lack of treatments available to prevent cell death, regenerate damaged cells and pathways, or promote neurogenesis.
Amanda J Craig, Gary D Housley
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source