Results 231 to 240 of about 170,400 (293)

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Protection against myocardial ischemia reperfusion injury by liquiritin: involvement of autophagy restoration targeting PIK3CA. [PDF]

Braz J Med Biol Res
Mao H, Li Z, Lu C.
europepmc   +1 more source

Erratum: BTLA deficiency promotes HSC activation and protects against hepatic ischemia-reperfusion injury

Shen Xiaoyun, Rongyun Mai, Xiao Han, Qi Wang, Yifan Wang, Tong Ji, Yifan Tong, Ping Chen, Jia Zhao, Xiaoyan He, Wen Tong, Rong Liang, Lin Yan, Xiaoling Luo, Xiujun Cai   +14 more
openalex   +1 more source

Circular RNA Foxo3 Relieves Myocardial Ischemia/Reperfusion Injury by Suppressing Autophagy via Inhibiting HMGB1 by Repressing KAT7 in Myocardial Infarction

, 2021
Guoming Sun, Shen JF, Wei XF, Qi GX
openalex   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Continuous pressure exacerbates ischemia-reperfusion injury in minipigs through the AKT/eNOS signaling pathway. [PDF]

Eur J Med Res
Tao L, Ma X, Yang Y, Wang H, Yang X, Luo Y.   +5 more
europepmc   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Role of HMGB1 in ischemia/reperfusion injury in a rat model of myocardial infarction. [PDF]

Sci Rep
Cebova M, Barta A, Bujnova K, Pechanova O.   +3 more
europepmc   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Cardiopulmonary bypass-mediated lung ischemia-reperfusion injury: A protective role of sitaxentan. [PDF]

J Int Med Res
Wang Z, Zhan R, Mo L, Zhang Y, Chen Y, Liu L, Bai Y.   +6 more
europepmc   +1 more source