Results 51 to 60 of about 931,368 (217)

Differential Expression and Bioinformatics Analysis of CircRNA in PDGF-BB-Induced Vascular Smooth Muscle Cells

Frontiers in Genetics, 2020
Atherosclerosis is mediated by various factors and plays an important pathological foundation for cardiovascular and cerebrovascular diseases.
Jiangtian Tian, Jiangtian Tian, Yahong Fu, Yahong Fu, Qi Li, Qi Li, Ying Xu, Ying Xu, Xiangwen Xi, Xiangwen Xi, Yuqi Zheng, Yuqi Zheng, Li Yu, Li Yu, Zhuozhong Wang, Zhuozhong Wang, Bo Yu, Jinwei Tian   +17 more
doaj   +1 more source

Trusting Machine Learning Results from Medical Procedures in the Operating Room [PDF]

AAAI workshop on Trustworthy AI for Healthcare 2022, 2022
Machine learning can be used to analyse physiological data for several purposes. Detection of cerebral ischemia is an achievement that would have high impact on patient care. We attempted to study if collection of continous physiological data from non-invasive monitors, and analysis with machine learning could detect cerebral ischemia in tho different ...
arxiv  

Novel insights into the cardio-protective effects of FGF21 in lean and obese rat hearts [PDF]

, 2014
Aims: Fibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic actions. Its plasma concentrations are increased in obesity and diabetes; states associated with an increased incidence of cardiovascular disease.
A Beenken, A Kharitonenkov, A Planavila, A Romero-Corral, A Sharma, AD Attie, AK Bose, Bee K. Tan, BK Tan, C Valina, C Yang, D Morabito, DJ Hausenloy, DR Riddell, E Braunwald, Edward W. Hillhouse, Emilio Hirsch, FM Fisher, G Nanayakkara, GC Rodrigo, GD Lopaschuk, H Jiao, H Li, Harpal S. Randeva, J Diaz-Delfin, J Mair, J Yie, J Yie, Jing Chen, JP Bertinchant, L Timmers, LC Clavijo, M Mraz, Manjunath Ramanjaneya, MC Mendoza, Muhammad F. Bari, N Shimizu, PK Shah, R Adya, R Mitra, Raghu Adya, S Doroudgar, S Kenchaiah, S Yusuf, SQ Liu, SQ Liu, Sunil K. Bhudia, T Matsui, T Nishimura, T Thim, T Uebanso, V Lionetti, Vanlata Patel, Y Ogawa, Y Wang   +54 more
core   +8 more sources

Modulation of Mitochondrial Bioenergetics in the Isolated Guinea Pig Beating Heart by Potassium and Lidocaine Cardioplegia: Implications for Cardioprotection [PDF]

, 2009
Mitochondria are damaged by cardiac ischemia/reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against ...
Aldakkak, Mohammed, Camara, Amadou K.S., Chen, Qun, Heisner, James S., Lesnefsky, Edward J., Stowe, David F.   +5 more
core   +2 more sources

ATF3 promotes ferroptosis in sorafenib-induced cardiotoxicity by suppressing Slc7a11 expression

Frontiers in Pharmacology, 2022
Sorafenib is the unique recommended molecular-targeted drug for advanced hepatocellular carcinoma, but its clinical use is limited due to cardiotoxicity.
Yilan Li, Yilan Li, Jingru Yan, Jingru Yan, Qianqian Zhao, Qianqian Zhao, Yan Zhang, Yao Zhang, Yao Zhang   +8 more
doaj   +1 more source

ATP-sensitive potassium channel subcellular trafficking during ischemia, reperfusion, and preconditioning [PDF]

, 2016
Ischemic preconditioning is an endogenous cardioprotective mechanism in which short periods of ischemia and reperfusion provide protection when given before a subsequent ischemic event.
Ho, Joanne Cin-Yee
core   +1 more source

Failed ISCHEMIA Trial or Failed Ischemia Testing? [PDF]

, 2020
The results of the ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approach) trial were presented at the American Heart Association Scientific Sessions in November, 2019 in Philadelphia, Pennsylvania, and ...
Budoff, Matthew J, Dahal, Suraj
core  

Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]

, 2006
FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Bohlen und Halbach, Oliver von, Dono, Rosanna, Kiprianova, Irina, Krause, Sonja, Schindowski, Katharina, Schwaninger, Markus, Unsicker, Klaus   +6 more
core  

FK 506 ameliorates the hepatic injury associated with ischemia and reperfusion in rats [PDF]

, 1991
The effect of FK 506 on regeneration of the liver was studied in rats after a two‐thirds partial hepatectomy after 60 min of ischemia of the unresected liver. The animals were divided into three distinct groups of 10 rats each.
Babaeva, Bergmeyer, Borel, Craddock, Craddock, Demetris, Farber, Flye, Francavilla, Francavilla, Gonzalez, Goto, Guzek, Higgins, Kahn, Kawano, Kim, Kim, Marubayashi, Marubayashi, Mazzaferro, Mazzaferro, Meer, Metzger, Miyahara, Ohhori, Sakai, Sakai, Sakai, Sobotka, Starzl, Stromski, Takahashi, Weeds, Yushimira   +34 more
core   +1 more source

Revisiting an old relationship: the causal associations of the ApoB/ApoA1 ratio with cardiometabolic diseases and relative risk factors—a mendelian randomization analysis

Cardiovascular Diabetology
Background It has been confirmed that the ApoB/ApoA1 ratio is closely associated with the incidence of cardiometabolic diseases (CMD). However, due to uncontrolled confounding factors in observational studies, the causal relationship of this association ...
Chao Fu, Dongbo Liu, Qi Liu, Xuedong Wang, Xiaoxue Ma, Hong Pan, Shi Feng, Zhao Sun, Weishen Qiao, Mengyue Yang, Shuang Gao, Hongyu Ding, Xingtao Huang, Jingbo Hou   +13 more
doaj   +1 more source