Unrecognized severe obstructive sleep apnea as a dominant risk factor for non-arteritic anterior ischemic optic neuropathy in an apparently healthy patient [PDF]
Vojnosanitetski PregledIntroduction. Non-arteritic anterior ischemic optic neuropathy (NAION) is typically manifested by sudden, pain-less vision loss in one eye, often immediately upon waking up.
Katanić-Pasovski Katarina +7 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
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Prognostic factors of functional outcome in acute ischemic stroke [PDF]
, 2013 Trombolyse is een behandeling waarbij een stolsel in een bloedvat wordt opgelost door het gebruik van anti-bloedstollingsmiddelen. Irene Miedema deed onderzoek naar veiligheidsaspecten van trombolyse.
Miedema, Irene, Miedema, Irene,
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Can the ischemic penumbra be identified on noncontrast CT of acute stroke? [PDF]
, 2007 <p><b>Background and Purpose:</b> Early ischemic changes on noncontrast CT in acute stroke include both hypoattenuation and brain swelling, which may have different pathophysiological significance.</p> <p><b>Methods:
Muir, K.W. +5 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]
, 2009 <p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Demchuk, A. +8 more
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Pharmacogenomics and Personalized Medicine, 2023 Yingqiu Wang, Renhua Hou, Yan Liu Department of Nuclear Medicine, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, 200090, People’s Republic of ChinaCorrespondence: Yingqiu Wang, Department of Nuclear Medicine, Yangpu Hospital, School of
Wang Y, Hou R, Liu Y
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
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Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
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Systematic ReviewsIntroduction Fibroblast activation protein-alpha (FAP-α) is a vital surface marker of cancer-associated fibroblasts, and its high expression is associated with distant metastasis.
Majid Janani +12 more
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