Results 161 to 170 of about 501,514 (279)

Insights Into Remote Ischemic Conditioning miRNA Effects on Brain Endothelial Cells During Ischemia-Reperfusion. [PDF]

Microcirculation
Stenz KT, Just J, Huang Z, Lassen TR, Vissing K, Wang XJ, Drasbek KR.   +6 more
europepmc   +1 more source

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Translational Barriers and Optimization Strategies for Remote Ischemic Conditioning to Enhance Stroke Cerebroprotection. [PDF]

Biomolecules
Zhang X, An J, Guo X, Li J, Wang R.
europepmc   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Remote ischemic conditioning in the thrombectomy era: The first step toward clinical neuroprotection? [PDF]

Brain Circ
Blauenfeldt RA.
europepmc   +1 more source

Remote ischemic conditioning in intensive care: From bench to bedside. [PDF]

Ann Intensive Care
Benghanem S, Stiel L, Jouan Y, Vedrenne-Cloquet M, Levy Y, Maldiney T, Sarton B, Kallel H, Bréchot N, Joffre J, Gallet R, Gaudet A, Kreitmann L.   +12 more
europepmc   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Remote Ischemic Conditioning for Acute Ischemic Stroke: The RICAIS Randomized Clinical Trial. [PDF]

J Atheroscler Thromb
Kitagawa K, Ishizuka K, Doijiri R, Maruyama K, Sakaguchi M, Hino S, Honma Y, Kimura Y, Iguchi Y, Hirano T, Oda M, Oi K, Toi S, Mizuno T, Arai S, Hosoya M, Wako S, Takahashi S, Saito M, Todo K, Saito T, Kimura K, Ago T, Kitazono T, Sato Y, Hoshino T, Remote Ischemic conditioning for Acute Ischemic Stroke (RICAIS) study group.   +26 more
europepmc   +1 more source