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Ischemic Optic Neuropathy: A Review of Current and Potential Future Pharmacotherapies [PDF]

Pharmaceuticals
The treatment of arteritic anterior ischemic optic neuropathy (AAION), non-arteritic ischemic optic neuropathy (NAAION), and posterior ischemic optic neuropathy (PION) is a topic of ongoing research with mixed evidence on some pharmacotherapies and a ...
Omar Badla, Beshr Abdulaziz Badla, Amr Almobayed, Carlos Mendoza, Krishna Kishor, Sanjoy K. Bhattacharya   +5 more
doaj   +3 more sources

Ischemic optic neuropathies: Current concepts

Annals of Indian Academy of Neurology, 2022
Ischemic optic neuropathy (ION) is the term ascribed to optic nerve disease that is the result of a transient or permanent interruption of the blood supply to any portion of the optic nerve. Anterior ischemic optic neuropathy (AION) refers to ischemia of
Ajay D Patil, Valerie Biousse, Nancy J Newman   +2 more
doaj   +3 more sources

Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy.

JAMA Ophthalmol
This cohort study investigates the association between semaglutide use and nonarteritic anterior ischemic optic neuropathy.
Cai CX, Hribar M, Baxter S, Goetz K, Swaminathan SS, Flowers A, Brown EN, Toy B, Xu B, Chen J, Chen A, Wang S, Lee C, Leng T, Ehrlich JR, Barkmeier A, Armbrust KR, Boland MV, Dorr D, Boyce D, Alshammari T, Swerdel J, Suchard MA, Schuemie M, Bu F, Sena AG, Hripcsak G, Nishimura A, Nagy P, Falconer T, DuVall SL, Matheny M, Viernes B, O'Brien W, Zhang L, Martin B, Westlund E, Mathioudakis N, Fan R, Wilcox A, Lai A, Stocking JC, Takkouche S, Lee LH, Xie Y, Humes I, McCoy DB, Adibuzzaman M, Areaux RG, Rojas-Carabali W, Brash J, Lee DA, Weiskopf NG, Mawn L, Agrawal R, Morgan-Cooper H, Desai P, Ryan PB.   +57 more
europepmc   +3 more sources

Use of semaglutide and risk of non-arteritic anterior ischemic optic neuropathy: A Danish-Norwegian cohort study. [PDF]

Diabetes Obes Metab
To investigate the putative association between semaglutide and non‐arteritic anterior ischaemic optic neuropathy (NAION).
Simonsen E, Lund LC, Ernst MT, Hjellvik V, Hegedüs L, Hamann S, Jørstad ØK, Gulseth HL, Karlstad Ø, Pottegård A.   +9 more
europepmc   +2 more sources

Nonarteritic anterior ischemic optic neuropathy: cause, effect, and management

Eye and Brain, 2017
Shauna Berry,1 Weijie V Lin,2 Ama Sadaka,1 Andrew G Lee1–7 1Department of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital, Houston, TX, USA; 2Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; 3Department of
Berry S, Lin WV, Sadaka A, Lee AG
doaj   +2 more sources

Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy Risk Among Patients With Diabetes.

JAMA Ophthalmol
Importance Recent studies have suggested an association between nonarteritic anterior ischemic optic neuropathy (NAION) with semaglutide usage. However, the limitations of those analyses warrant further investigation, given the frequency of use of these ...
Hsu AY, Kuo HT, Wang YH, Lin CJ, Shao YC, Chiang CC, Hsia NY, Lai CT, Tseng H, Wu BQ, Chen HS, Tsai YY, Hsu MY, Wei JC.   +13 more
europepmc   +2 more sources

Arteritic anterior ischemic optic neuropathy secondary to immune checkpoint inhibitors: A case report [PDF]

Radiology Case Reports
Ischemic optic neuropathy (ION) occurs due to insufficient blood supply to the optic nerve, with anterior ischemic optic neuropathy (AION) commonly associated with giant cell arteritis (GCA).
Zahin Alam, BS, Tausif Ahmed Siddiqui, BS, Mohammed Usman Syed, BS, Pavan K. Kottamasu, MD, Tushar Nag, Akm Rahman, MD, DO   +5 more
doaj   +2 more sources

Valosin-containing protein modulator KUS121 protects retinal neurons in a rat model of anterior ischemic optic neuropathy [PDF]

Scientific Reports
Ischemic optic neuropathy is a leading cause of sudden vision loss, particularly in elderly individuals, with no available effective treatments. Ischemia-induced irreversible damage to optic nerve fibers highlights the need for novel therapies with ...
Chinami Kikkawa, Hanako Ohashi Ikeda, Masayuki Hata, Sachiko Iwai, Akitaka Tsujikawa   +4 more
doaj   +2 more sources

A 54-year-old male with posterior ischemic optic neuropathy misdiagnosed as ophthalmic artery occlusion [PDF]

BMC Ophthalmology
Purpose To describe a case of non-arteritic posterior ischemic optic neuropathy (NA-PION). Observations One 54-year-old male with a history of hypertension and poor blood pressure control suffered from sudden decreases in color vision and vision over ...
Yuman Li, Ying Cui, Zhixin Mo, Xiaofeng Huang, Mingsi Chi, Tai Guo, Zhongning Huang   +6 more
doaj   +2 more sources

Ischemic optic neuropathy following craniotomy

Journal of Nepal Health Research Council, 2023
Ischemic optic neuropathy is one of the major causes of severe impairment of vision often leading to blindness. It has varied etiopathogenesis with limited management options and very often result in poor outcome. Perioperative ischemic optic neuropathy
Ranjit Kumar Chaudhary, Sanjib Kumar Chaudhary, Elina Gupta, Karthikram Raghuram   +3 more
doaj   +1 more source