Results 181 to 190 of about 8,004 (220)

Ischemic postconditioning during primary percutaneous coronary intervention

Catheterization and Cardiovascular Interventions, 2017
BackgroundAlthough some studies have shown potential benefit for ischemic postconditioning (IPoC) during primary percutaneous coronary intervention (PCI) in improving surrogate markers of reperfusion and infarction size, the benefit of this approach on clinical outcomes remains unknown.Methods and ResultsElectronic databases were searched for ...
Amgad Mentias, Ahmed N. Mahmoud, Islam Y. Elgendy, Akram Y. Elgendy, Amr F. Barakat, A. Sami Abuzaid, Marwan Saad, Samir R. Kapadia   +7 more
openaire   +2 more sources

Connexin 43 in ischemic pre- and postconditioning

Heart Failure Reviews, 2007
Connexin 43 (Cx43) is the predominant protein forming gap junctions and non-junctional hemichannels in ventricular myocardium, but Cx43 is also localized at the inner membrane of cardiomyocyte mitochondria. In cardiomyocytes, Cx43 is involved in the formation of reactive oxygen species, which are central to the signal transduction cascade of ischemic ...
Rainer, Schulz, Kerstin, Boengler, Andreas, Totzeck, Yukun, Luo, David, Garcia-Dorado, Gerd, Heusch   +5 more
openaire   +2 more sources

Ischemic Postconditioning: From Receptor to End-Effector

Antioxidants & Redox Signaling, 2011
Ischemic preconditioning, a robust cardioprotective intervention, has limited clinical efficacy because it must be initiated before myocardial ischemia. Conversely, ischemic postconditioning, repeated brief reocclusions of a coronary artery after release of prolonged coronary occlusion, provides cardioprotection in clinically feasible settings, that is,
Michael V, Cohen, James M, Downey
openaire   +2 more sources

Ischemic Postconditioning Attenuates Renal Ischemic/Reperfusion Injury in Mongrel Dogs

Urology, 2010
To investigate the effect of Postcond on renal ischemia-reperfusion (I/R) injury in a canine model. I/R injury is the most common cause of renal dysfunction. Ischemic postconditioning (Postcond) is a phenomenon by which intermittent interruptions of blood flow in the early phase of reperfusion can protect organs from I/R injury.Forty adult male mongrel
Botao, Jiang, Xiuheng, Liu, Hui, Chen, Dongshan, Liu, Youling, Kuang, Bianzhi, Xing, Zhiyuan, Chen   +6 more
openaire   +2 more sources

Determining the optimal time to introduce ischemic postconditioning

Expert Review of Cardiovascular Therapy, 2011
ST-segment elevation myocardial infarction (STEMI) is a major cause of death and heart failure in Western society [1].
Lønborg, Jacob, Engstrøm, Thomas
openaire   +3 more sources

[Ischemic pre- and postconditioning].

Deutsche medizinische Wochenschrift (1946), 2006
One or several short cycles of ischemia/reperfusion before (preconditioning) or after (postconditioning) a sustained coronary occlusion with subsequent reperfusion reduce the ultimate infarct size. The protection is potent, but limited to a narrow time frame.
G, Heusch, R, Schulz
openaire   +1 more source

Different ischemic duration and frequency of ischemic postconditioning affect neuroprotection in focal ischemic stroke

Journal of Neuroscience Methods, 2020
Many studies have confirmed that "in situ ischemia postconditioning" (ISPostC) and "remote ischemic postconditioning" (RIPostC) can reduce cerebral ischemia/reperfusion injury, but there is no comparison was made on the consistency of neuroprotection in ISPostC and RIPostC to different ischemic duration and number of cycles.We used a transient middle ...
Chun-Yan, Li, Wei, Ma, Kuang-Pin, Liu, Jin-Wei, Yang, Xian-Bin, Wang, Zhen, Wu, Tong, Zhang, Jia-Wei, Wang, Wei, Liu, Jie, Liu, Yu, Liang, Xing-Kui, Zhang, Jun-Jun, Li, Jian-Hui, Guo, Li-Yan, Li   +14 more
openaire   +2 more sources

[Phenomenon of heart ischemic postconditioning].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2012
Authors of review analyzed papers on problem of heart ischemic postconditioning. In the review, it was demonstrated that postconditioning decreased an infarct size, prevented cardiomyocytes apoptosis, improved cardiac contractility in reperfusion period, augmented cardiac tolerance to arrhythmogenic impact ofreperfusion, prevented neutrophil invasion ...
L N, Maslov, A G, Mrochek, L, Hanus, J -M, Pei, Y, Zhang, H, Wang, N V, Naryzhnaia   +6 more
openaire   +1 more source

Ischemic postconditioning altered microRNAs in human valve replacement

Journal of Surgical Research, 2016
Although the involvement of microRNAs (miRNAs) has been intensively studied in myocardial infarction, there is no report on the regulation of miRNAs by ischemic postconditioning in patients undergoing cardiac surgery. We aim to explore the regulation of miRNAs by ischemic postconditioning in double valve replacement.In this prospective, controlled ...
Yang, Gao, Rimao, Huang, Ri, Chen, Jun, Li, Wanjun, Luo   +4 more
openaire   +2 more sources

Protection Against Renal Ischemia-Reperfusion Injury by Ischemic Postconditioning

Transplantation, 2013
Ischemia-reperfusion injury (IRI) is inevitable during transplantation. Attempts to reduce IRI have mainly focused on ways to improve hypothermic organ preservation and reduce the nephrotoxic effects of calcineurin inhibitors. Recently, it has been shown that short, repeated sequences of intermittent ischemia and reperfusion after a prolonged ischemic ...
Akker, Eline, Manintveld, Olivier, Hesselink, Dennis, de Bruin, Ron, IJzermans, J.N.M., Dor, Frank   +5 more
openaire   +3 more sources