Integrity of Cerebellar Fastigial Nucleus Intrinsic Neurons Is Critical for the Global Ischemic Preconditioning [PDF]
Excitation of intrinsic neurons of cerebellar fastigial nucleus (FN) renders brain tolerant to local and global ischemia. This effect reaches a maximum 72 h after the stimulation and lasts over 10 days.
Eugene V. Golanov +2 more
doaj +2 more sources
Remote ischemic preconditioning [PDF]
Since cardiac surgery began, surgeons have aimed to find methods of minimizing myocardial injury resulting from ischemia and reperfusion. The concept of somehow conditioning the heart in order to attenuate ischemia and reperfusion-related injury has evolved in cardiovascular research over decades, from ischemic preconditioning and postconditioning to ...
Thielmann, Matthias Klaus +6 more
+6 more sources
Ischemic preconditioning [PDF]
Background. Ischemic preconditioning is a phenomenon during which myocardium, subjected to brief episodes of ischemia followed by reperfusion, tolerates better the subsequent, more prolonged episode of this ischemia, thus reducing the infarction size ...
Ristić-Anđelkov Anđelka +3 more
doaj +3 more sources
Ischemic preconditioning and clinical scenarios [PDF]
Ischemic preconditioning (IPC) is gaining attention as a novel neuroprotective therapy and could provide an improved mechanistic understanding of tolerance to cerebral ischemia. The purpose of this article is to review the recent work in the field of IPC and its applications to clinical scenarios.The cellular signaling pathways that are activated ...
Srinivasan V, Narayanan +2 more
openaire +4 more sources
Ischemic preconditioning protects against ischemic brain injury
In this study, we hypothesized that an increase in integrin αv ß 3 and its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning with bilateral common carotid artery
Xiao-meng Ma +5 more
doaj +3 more sources
Effects of ischemic preconditioning and cilostazol on muscle ischemia-reperfusion injury in rats [PDF]
PURPOSE: To evaluate effects of ischemic preconditioning and Cilostazol on muscle ischemia-reperfusion injury. METHODS: Male Wistar rats were submitted to muscle ischemic and reperfusion injury (4h of the left common iliac artery occlusion followed by 1h
Carlos Alberto da Silva Frias Neto +4 more
doaj +5 more sources
Impact of combined ischemic preconditioning and melatonin on renal ischemia-reperfusion injury in rats [PDF]
Objective(s): Studying the effect of melatonin pretreatment and ischemic preconditioning on renal ischemia-reperfusion injury (IRI). Materials and Methods: Forty-eight Wistar rats were randomized into six groups: control, sham operation, IRI (IRI in left
Hesham Abdel-Razek +5 more
doaj +1 more source
Protective effects of treprostinil and ischemic preconditioning on hepatic ischemia-reperfusion injury and biomarkers in experimental studies in rats. [PDF]
Mouratidou C +9 more
europepmc +2 more sources
Ischemic preconditioning modifies mortality and inflammatory response [PDF]
PURPOSE: To evaluate the effect of ischemic preconditioning on mortality, inflammatory mediators and oxidative stress after intestinal ischemia and reperfusion.
Daniel Faria de Campos Pinheiro +7 more
doaj +2 more sources
Effect of Remote Ischemic Preconditioning on Patient Survival and End Organ Injury During Elective Open Abdominal Aortic Surgery Repair: A Randomized Controlled Trial [PDF]
Background: Ischemic preconditioning is natural cytoprotective mechanism that can potentially protect end organs from ischemia. In examined instances having major vascular surgery, remote ischemia preconditioning provides straight-forward technique with ...
Mohamed Abdallah, Abdelrahman Elnaggar
doaj +1 more source

